(1R,2S)-2-Amino-1,2-Diphenylethanol (1R,2S)-2-氨基-1,2-二苯基乙醇

CAS 23190-16-1 MFCD00074960

化学结构图

23190-16-1
SMILES: N[C@@H](c1ccccc1)[C@H](O)c1ccccc1

化学属性

Mol. FormulaC14H15NO
Mol. Weight213
Melting Point143.0 to 146.0 deg-C
TSCANo

别名和识别编码

Chemical Name(1R,2S)-2-Amino-1,2-Diphenylethanol
CAS Number23190-16-1
Alfabeta NameAMINODIPHENYLETHANOL RS12212()----,,
MDL NumberMFCD00074960
Synonym (?R,?S)-?-Amino-?-phenylbenzeneethanol (1R,2S)-2-Amino-1,2-diphenylethanol (1R,2S)-erythro-(-)-2-Amino-1,2-diphenylethanol (1R,2S)-Diphenyl-2-aminoethanol (1R,2S)-1,2-Diphenyl-2-aminoethanol (1R,2S)-(-)-2-氨基-1,2-二苯乙醇 (1R,2S)-2-氨基-1,2-二苯基乙醇
Beilstein Registry Number2806218
PubChem Substance ID87562700
Chemical Name Translation(1R,2S)-2-氨基-1,2-二苯基乙醇
Reaxys-RN2806218
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分类

  • {SNA} Amino Alcohols, Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Organic Building Blocks
  • Heterocycles
  • Pharmaceuticals
  • Amines
  • Intermediates & Fine Chemicals
  • Aromatics

产品应用

  • (1R,2S)-(-)-2-Amino-1,2-diphenylethanol is a hydroxylated 1,2-diphenethylamine derivative with affinity for the NMDA receptor.

相关文献及参考

  • Berger, M.L. et al.: Bioorg. Med. Chem., 17, 3456 (2009);

安全信息

Warnings IRRITANT
GHS Symbol
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P302+P352+P332+P313+P362+P364
  • P332+P313
  • P305+P351+P338+P337+P313
  • P302+P350
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
  • P337+P313
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word Warning
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Hazard Codes Xi

系列性分类

  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块
  4. Organic Building Blocks - Chiral Building Blocks
  5. Amino Alcohols - Organic Building Blocks
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块
  4. Organic Building Blocks - Chiral Building Blocks
  5. Amino Alcohols - Organic Building Blocks
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Organic Building Blocks 有机砌块
  4. Oxygen Compounds 氧化合物
  5. Aromatic alcohols 芳香醇
  1. Chemical Synthesis 化学合成
  2. Synthetic Reagents 合成试剂
  3. Optical Resolution
  1. Chemical Synthesis 化学合成
  2. Asymmetric Synthesis 不对称合成
  3. Chiral Building Blocks 手性分子砌块

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