[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Et-Tyr2, Val4, Arg8]-Vasopressin

CAS 77453-01-1 MFCD00076752

化学结构图

77453-01-1
SMILES: CC(C)[C@@H]1NC(=O)[C@H](CC2C=CC=CC=2)NC(=O)[C@H](CC2C=CC(=CC=2)OCC)NC(=O)CC2(CCCCC2)SSC[C@H](NC(=O)[C@H](CC(N)=O)NC1=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O

化学属性

Mol. FormulaC53H75N13O11S2
Mol. Weight1134.37

别名和识别编码

Chemical Name[β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Et-Tyr2, Val4, Arg8]-Vasopressin
MDL NumberMFCD00076752
CAS Number77453-01-1
Synonym [β-Mercapto-β,β-cyclopentamethylenepropionyl1, O-Et-Tyr2, Val4, Arg8]-Vasopressin
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分类

  • Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Oxytocin & Vasopressin, Peptides and Proteins, Peptides for Cell Biology, Pituitary Hormones, V, Vasopressin, Vasopressins
  • {SNA} Cytokines, Growth Factors and Hormones, Hormones, Oxytocin & Vasopressin, Peptides and Proteins, Peptides for Cell Biology, Pituitary Hormones, Vasopressin, Vasopressins, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factor

相关文献及参考

  • Ammar, A., et al., Pharmacological characterization of V1a vasopressin receptors in the rat cortical collecting duct. Am. J. Physiol. 262 , F546-F553, (1992) 摘要
  • Champigneulle, A., et al., V2-like vasopressin receptor mobilizes intracellular Ca 2+ in rat medullary collecting tubules. Am. J. Physiol. 265 , (1993)
  • Chan, W.Y., et al., Discovery and design of novel and selective vasopressin and oxytocin agonists and antagonists: the role of bioassays. Exp. Physiol. 85 , 7S-18S, (2000) 摘要
  • Manning, M., et al., Position three in vasopressin antagonist tolerates conformationally restricted and aromatic amino acid substitutions: a striking contrast with vasopressin agonists. J. Pept. Sci. 3 , 31-46, (1997) 摘要
  • [1]. S Ishikawa, et al. Further in vivo evidence for antagonist-to-antidiuretic action of arginine vasopressin. Am J Physiol. 1983 Nov;245(5 Pt 1):R713-9.

安全信息

GHS Symbol
WGK Germany3
Signal word Warning
Hazard statements
  • H332 Harmful if inhaled 吸入有害
Hazard Codes Xn
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R20 Harmful by inhalation 吸入有害

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Pituitary Hormones - Hormones
  7. Vasopressin - Pituitary Hormones
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Cytokines, Growth Factors and Hormones - Cell Signaling and Neuroscience
  5. Hormones - Cytokines, Growth Factors and Hormones
  6. Pituitary Hormones - Hormones
  7. Vasopressin - Pituitary Hormones
  1. Oxytocin & Vasopressin - Peptides for Cell Biology
  2. Vasopressins - Oxytocin & Vasopressin
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Vasopressin Receptor  (血管加压素受体)

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