CAS 91224-37-2 MFCD00076805

化学结构图

91224-37-2
SMILES: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC1=CNC2C=CC=CC1=2)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@@H](CC1=CNC2C=CC=CC1=2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)CCCNC(N)=N)C(N)=O

化学属性

Mol. FormulaC75H108N20O13
Mol. Weight1497.79

别名和识别编码

Chemical Name
Synonym [D-Arg1, D-Trp7,9, Leu11]-Substance P
MDL NumberMFCD00076805
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分类

  • {SNA} Antagonist, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Peptides and Proteins, Peptides for Cell Biology, S, Tachykinins

相关文献及参考

  • [2]. M Zubrzycka, et al. Comparison of antagonistic properties of substance P analogs, spantide I, II and III, on evoked tongue jerks in rats. Endocr Regul. 2000 Mar;34(1):13-8.
  • [3]. Linda D Hazlett, et al. Spantide I decreases type I cytokines, enhances IL-10, and reduces corneal perforation in susceptible mice after Pseudomonas aeruginosa infection. Invest Ophthalmol Vis Sci. 2007 Feb;48(2):797-807.
  • [1]. J C Beaujouan, et al. Higher potency of RP 67580, in the mouse and the rat compared with other nonpeptide and peptide tachykinin NK1 antagonists. Br J Pharmacol. 1993 Mar;108(3):793-800.
  • [1]. J C Beaujouan, et al. Higher potency of RP 67580, in the mouse and the rat compared with other nonpeptide and peptide tachykinin NK1 antagonists. Br J Pharmacol. 1993 Mar;108(3):793-800.
  • [2]. M Zubrzycka, et al. Comparison of antagonistic properties of substance P analogs, spantide I, II and III, on evoked tongue jerks in rats. Endocr Regul. 2000 Mar;34

安全信息

WGK Germany3

系列性分类


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