Prostaglandin D2 Lipid Maps MS Standard

CAS 41598-07-6 MFCD00077857

化学结构图

41598-07-6
SMILES: CCCCC[C@@H](O)/C=C/[C@H]1[C@H](C/C=C\CCCC(O)=O)C(=O)C[C@@H]1O |&1:5,9,10,23|

化学属性

Mol. FormulaC20H32O5
Mol. Weight352.47

别名和识别编码

Chemical NameProstaglandin D2
Synonym (5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid PGD2 (5Z,9α,13E,15S)-9,15-Dihydroxy-11-oxoprosta-5,13-dien-1-oic-acid PGD2 11-Dehydroprostaglandin F2-alpha PGD2 Prostaglandin D2
MDL NumberMFCD00077857
PubChem Substance ID24898605
Beilstein Registry Number2170623
CAS Number41598-07-6
Wiswesser Line NotationT5VTJ B1U7 C2U4VQ DQ
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Bioactive Small Molecules, Biochemicals and Reagents,
  • {SA} Arachidonic Acid Cascade, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Eicosanoids (Prostaglandins, Leukotrienes), Fatty Acyls, Lipids, Lipids in Cell Signaling, P, Prostaglandins
  • Arachidonic Acid Cascade,
  • {SNA} Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Eicosanoids (Prostaglandins, Leukotrienes), Fatty Acyls, Lipids in Cell Signaling, PI-PZ, Prostaglandins, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 脂类

相关文献及参考

  • [2]. Zhang BJ, et al. Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 in mice. Acta Pharmacol Sin. 2017 Apr;38(4):469-476.
  • [3]. Kida T, et al. Prostaglandin D2 Attenuates NSC 125066-Induced Lung Inflammation and Pulmonary Fibrosis. PLoS One. 2016 Dec 19;11(12):e0167729.
  • Giles, H., and Leff, P. Prostaglandins 35 , 277, (1988) 摘要
  • Hayaishi, O. J. Biol. Chem. 263 , 14593, (1988) 摘要
  • [1]. Suzuki F, et al. Transport of prostaglandin D2 into brain. Brain Res. 1986 Oct 22;385(2):321-8.
  • [1]. Suzuki F, et al. Transport of prostaglandin D2 into brain. Brain Res. 1986 Oct 22;385(2):321-8.
  • [2]. Zhang BJ, et al. Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 in mice. Acta Pharmacol Sin. 2017 Apr;38(4):469-476.
  • [3]. Kida T, et al. Prostaglandin D2 Attenuates NSC 125066-Induced Lung Inflammation and Pulmonary Fibrosis. PLoS One. 2016 Dec 19;11(12):e016772

安全信息

WGK Germany3
Precautionary statements
  • P308+P313
  • P201 Obtain special instructions before use. 使用前获取专门指示。
RTECSUK7930000
Hazard statements
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H302 Harmful if swallowed 吞食有害
Hazard Codes T
GHS Symbol
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Signal word Danger
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
  • S22 Do not breathe dust 不要吸入粉尘；
Risk Statements
  • R60 May impair fertility 可能降低生殖能力
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 5 mg/L/24H
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,1688,1986

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Ascites tumor
DOSE/DURATION           : 2 mg/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,3364,1986

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Ascites tumor
DOSE/DURATION           : 1 mg/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,3364,1986

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 5 mg/L/24H
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,1688,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 400 ug/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,790,1983

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Fatty Acyls - Lipids
  5. Eicosanoids (Prostaglandins, Leukotrienes) - Fatty Acyls
  6. Prostaglandins - Eicosanoids (Prostaglandins, Leukotrienes)
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Lipids - Biochemicals and Reagents
  4. Fatty Acyls - Lipids
  5. Eicosanoids (Prostaglandins, Leukotrienes) - Fatty Acyls
  6. Prostaglandins - Eicosanoids (Prostaglandins, Leukotrienes)
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Prostaglandin Receptor  (前列腺素受体)
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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