Hycon
CAS 143-71-5 MFCD00078557
化学结构图
SMILES: COc1ccc2c3c1O[C@H]1C(=O)CC[C@H]4[C@@H](C2)N(C)CC[C@]314.O=C(O)C(O)C(O)C(=O)O
化学属性
| Mol. Formula | C18H21NO3· C4H6O6 |
|---|---|
| Mol. Weight | 449.45 |
别名和识别编码
| Chemical Name | |
|---|---|
| Synonym | 4,5-Epoxy-3-methoxy-17-methyl-5α-morphinan-6-one (2R,3R)-2,3-dihydroxybutanedioate (1:1) Codinovo Dicodid Dihydrocodeinone Hycodan Hycon Hydrocodeinonebitartrate Hydrocodon Hydrocodone Hydrocodone (+)-bitartrate salt Hydrocodone Bitartrate Hydrocodone Tartrate (1:1), Hydrate (2:5) Hydrocon Robidone |
| MDL Number | MFCD00078557 |
| PubChem Substance ID | 5463977 |
| CAS Number | 143-71-5 |
| EC Number | 205-608-1 |
| InChI | InChI=1S/C18H21NO3.C4H6O6/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19;5-1(3(7)8)2(6)4(9)10/h3,6,11-12,17H,4-5,7-9H2,1-2H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-,12+,17-,18-;1-,2-/m01/s1 |
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分类
- Abbott, Alkaloids, Alphabetic, Analytical Standards, Analytical/Chromatography, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, Excitatory Amino Acids - Opiod Agonists, Forensic and Veterinary Standards, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, H, HU - HZ, Membrane Protein Biology Tools, Morphine, Neat Compounds, Neurobiology, Neuroscienc
相关文献及参考
- Kotzer, C.J., et al., The antitussive activity of delta-opioid receptor stimulation in guinea pigs. J. Pharmacol. Exp. Ther. 292 , 803-809, (2000) 摘要
- Tomkins, D.M., et al., Effect of cytochrome P450 2D1 inhibition on hydrocodone metabolism and its behavioral consequences in rats. J. Pharmacol. Exp. Ther. 280 , 1374-1382, (1997) 摘要
- Chen, Z.R., et al., Mu receptor binding of some commonly used opioids and their metabolites. Life Sci. 48 , 2165-2171, (1991) 摘要
- Merck 14 ,4785
安全信息
- H300 Fatal if swallowed 吞食致命
- H301 Toxic if swallowed 吞食有毒
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H330 Fatal if inhaled 吸入致命
- H331 Toxic if inhaled 吸入中毒
- H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
- H336 May cause drowsiness or dizziness 肯能导致嗜睡或头晕
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P272 Contaminated work clothing should not be allowed out of the workplace. 污染的工作服不得带出工作场所。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P284 Wear respiratory protection.? 佩戴呼吸保护装置。
- P285 In case of inadequate ventilation wear respiratory protection. 在通风不足的情况下，戴呼吸防护。
- P301+P310
- P301+P312
- P302+P352
- P304+P340
- P304+P341
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
- P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
- P320 Specific treatment is urgent (see … on this label). 紧急具体治疗（见本标签上的）。
- P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
- P322 Specific measures (see …on this label). 具体治疗（见本标签上的）。
- P330 Rinse mouth. 漱口
- P333+P313
- P342+P311
- P363 Wash contaminated clothing before reuse. 被污染的衣服洗净后方可重新使用。
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
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