2-(4-(4-(2-Methoxyphenyl)Piperazin-1-Yl)Butyl)Isoindoline-1,3-Dione Hydrobromide 2-(4-(4-(2-甲氧基苯基)哌嗪-1-基)丁基)异吲哚啉-1,3-二酮氢溴酸盐

CAS 115338-32-4 MFCD00078590

化学结构图

115338-32-4
SMILES: Br.COC1=CC=CC=C1N1CCN(CCCCN2C(=O)C3=CC=CC=C3C2=O)CC1

化学属性

Mol. FormulaC23H27N3O3· HBr
Mol. Weight474.39

别名和识别编码

Chemical Name2-(4-(4-(2-Methoxyphenyl)Piperazin-1-Yl)Butyl)Isoindoline-1,3-Dione Hydrobromide
Synonym 1-(2-Methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine hydrobromide NAN-190 hydrobromide
MDL NumberMFCD00078590
PubChem Substance ID24278108
Chemical Name Translation2-(4-(4-(2-甲氧基苯基)哌嗪-1-基)丁基)异吲哚啉-1,3-二酮氢溴酸盐
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分类

  • {SNA} Antagonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, N, Neuroscience, Neurotransmission, Neurotransmitters, Proteins and Derivatives, Serotonergics, Serotonergics - Antagonists
  • {SNA} Antagonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Serotonergics, Serotonergics - Antagonists, 生化试剂

相关文献及参考

  • [2]. Sharifi H, et al. Dose-Dependent Effect of Flouxetine on 6-OHDA-Induced Catalepsy in Male Rats: A Possible Involvement of 5-HT1A Receptors. Adv Pharm Bull. 2013;3(1):203-6.
  • [3]. Citó MC, et al. Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice: evidence for involvement of the monoaminergic system. Braz J Med Biol Res. 2015 Jan;48(1):57-64.
  • [1]. Shahane SA, et al. Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. J Biomol Screen. 2014 Jan;19(1):66-76.
  • [1]. Shahane SA, et al. Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. J Biomol Screen. 2014 Jan;19(1):66-76.
  • [2]. Sharifi H, et al. Dose-Dependent Effect of Flouxetine on 6-OHDA-Induced Catalepsy in Male Rats: A Possible Involvement of 5-HT1A Receptors. Adv Pharm Bull. 2013;3(1):203-6.
  • [3]. Citó MC, et al. Antidepressant-like effect of Hoodia go

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi,N
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R50 Very toxic to aquatic organisms 对水生生物极毒

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Bioactive Small Molecules - Cell Biology
  4. N - Bioactive Small Molecules
  1. Medical Research Areas
  2. GPCR & G Protein
  3. 5-HT Receptor  (5-羟色胺受体)
  1. Medical Research Areas
  2. GPCR & G Protein
  3. 5-HT Receptor  (5-羟色胺受体)
  4. 5-HT Receptor  (5-羟色胺受体)
  5. 5-HT Receptor  (5-羟色胺受体)
  6. 5-HT Receptor  (5-羟色胺受体)
  7. 5-HT Receptor  (5-羟色胺受体)

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