Flurandrenolide 氟氢缩松
CAS 1524-88-5 MFCD00079290
化学结构图
SMILES: CC1(C)O[C@@H]2C[C@H]3[C@@H]4C[C@H](F)C5=CC(=O)CC[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1
化学属性
| Mol. Formula | C24H33FO6 |
|---|---|
| Mol. Weight | 437 |
别名和识别编码
| Chemical Name | Flurandrenolide |
|---|---|
| CAS Number | 1524-88-5 |
| Synonym | ######## 6α-Fluoro-11β,16α,17,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide 6α-Fluoro-11β,16α,17,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide Fludroxycortide Alondra-F Cordran Drenison Drocort Fluorandrenolone Fluorandrenolone acetonide Fluoroandrenolone acetonide Flurandrenolide Flurandrenolone Flurandrenolone acetonide Glucocorticoid Haelan Haldrone-F L 33379 Sermaka 氟氢缩松 |
| MDL Number | MFCD00079290 |
| PubChem Substance ID | 15209 |
| EC Number | 216-196-8 |
| Chemical Name Translation | 氟氢缩松 |
| Wiswesser Line Notation | T F5 E5 B666 GO IO RV PUTJ A1 CQ E1 FV1Q H1 H1 OF |
| LabNetwork Molecule ID | LN01297487 |
| InChI | InChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1 |
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分类
- {SNA} Corticosteroid, Cytokines, Growth Factors and Hormones, Hormones, Steroid Hormones, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Cell Biology, Cell Signaling and Neuroscience, Corticosteroid, Cytokines, Growth Factors and Hormones, Hormones, Steroid Hormones
- Steroids
- Pharmaceuticals
- {SNA} Cell Signaling and Neuroscience, Corticosteroid, Cytokines, Growth Factors and Hormones, Hormones, Steroid Hormones, 细胞生物学
- Intermediates & Fine Chemicals
产品应用
- Glucocorticoid; antipsoriatic.
相关文献及参考
- Pearlman, R., et al.: Int. J. Pharm., 18, 53 (1984),
- Neufeld, E., et al.: J. Chromatogr., 718, 273 (1998),
安全信息
WGK Germany3
GHS Symbol
Precautionary statements
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P264+P265
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P337+P313
- P337+P317
Hazard statements
- H319 Causes serious eye irritation 严重刺激眼睛
RTECSTU5024800
Signal word
Warning
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
TYPE OF TEST : Mutation test systems - not otherwise specified ROUTE OF EXPOSURE : Administration onto the skin TEST SYSTEM : Human DOSE/DURATION : 19 mg/kg REFERENCE : 26UYA8 "Psoriasis, Proceedings of the International Symposium, Stanford, CA, 1971," Farber, E.M., and A.J. Cox, eds., Stanford, CA, Stanford Univ. Press, 1971 Volume(issue)/page/year: -,335,1971
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