PGLU-D-PHE-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2

CAS 54784-44-0 MFCD00079994

化学结构图

54784-44-0
SMILES: CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2C=CC=CC=21)NC(=O)[C@@H](CC1C=CC=CC=1)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)NCC(N)=O

化学属性

Mol. FormulaC59H79N15O13
Mol. Weight1206.53

别名和识别编码

Chemical NameLuteinizing hormone-releasing hormone, (D-phe(sup2))-(D-ala(sup 6))-
MDL NumberMFCD00079994
Synonym Luteinizing hormone-releasing hormone (pig),
CAS Number54784-44-0
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分类

  • {SA} Cell Biology, Cell Signaling and Neuroscience, LH-RH, Peptides and Proteins, Peptides for Cell Biology, Releasing Factors

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P308+P313
  • P201 Obtain special instructions before use. 使用前获取专门指示。
Hazard statements
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
RTECSOK6600000
Signal word Danger
Personal Protective Equipment Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE                    : 12500 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   EDRCAM Endocrine Research Communcations.  (New York, NY)  V.1-9, 1974-83.
   Volume(issue)/page/year: 2,1,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 30 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   EDRCAM Endocrine Research Communcations.  (New York, NY)  V.1-9, 1974-83.
   Volume(issue)/page/year: 2,1,1975

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2500 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   IJGOAL International Journal of Gynaecology & Obstetrics.  (Elsevier
   Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland)  V.7-    1969-
   Volume(issue)/page/year: 16,359,1979

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3750 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Wash

系列性分类

  1. Releasing Factors - Peptides for Cell Biology
  2. LH-RH - Releasing Factors

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