DELTORPHIN II
CAS 122752-16-3 MFCD00080072
化学结构图
SMILES: C[C@@H](NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCC(N)=O
化学属性
| Mol. Formula | C38H54N8O10 |
|---|---|
| Mol. Weight | 782.88 |
别名和识别编码
| Chemical Name | [D-Ala2]-Deltorphin II |
|---|---|
| Synonym | Tyr-D-Ala-Phe-Glu-Val-Val-Gly amide |
| MDL Number | MFCD00080072 |
| PubChem Substance ID | 24899907 |
| CAS Number | 122752-16-3 |
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分类
- {SNA} Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, D-DIF, Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology
- Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, D-DIF, Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology
相关文献及参考
- Melchiorri, P., et al., Long-term sensitization to the activation of cerebral delta-opioid receptors by the deltorphin Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2 in rats exposed to morphine. Proc. Natl. Acad. Sci. U. S. A. 89 , 3696-3700, (1992) 摘要
- Thomas, S.A., Structure-activity relationships of a series of [D-Ala 2 ]-deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability. J. Pharmacol. Exp. Ther. 281 , 817-825, (1997)
- Tsuji, M., et al., Region-dependent G-protein activation by mu-, delta 1- and delta 2-opioid receptor agonists in the brain: comparison between the midbrain and forebrain. Life Sci. 65 , PL233-PL239, (1999)
- [1]. Thomas SA, et al. Structure-activity relationships of a series of [D-Ala2]deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability. J Pharmacol Exp Ther. 1997 May;281(2):817-25.
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