Streptokinase from β-hemolytic Streptococcus (Lancefield Group C) Streptokinase
CAS 9002-01-1 MFCD00082037
化学结构图
SMILES: O=C(O)C1CC(C2CCCCC2)CN1
别名和识别编码
| Synonym | Streptase Kabikinase Streptococcal fibrinolysin Streptokinase 来源于溶血性链球菌 Streptokinase 来源于 β-溶血性链球菌 （兰斯费氏菌 C 群） Streptokinase Awelysin |
|---|---|
| MDL Number | MFCD00082037 |
| CAS Number | 9002-01-1 |
| Chemical Name Translation | Streptokinase |
| Chemical Name | Streptokinase from beta-hemolytic Streptococcus (Lancefield Group C) lyophilized powder, >=3,000 units/mg solid |
| EC Number | 232-647-1 |
| PubChem Substance ID | 9815560 |
| InChI | InChI=1S/C11H19NO2/c13-11(14)10-6-9(7-12-10)8-4-2-1-3-5-8/h8-10,12H,1-7H2,(H,13,14) |
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分类
- {SNA} 3.4.x.x Peptidases, 3.x.x.x Hydrolases, Application Index, Biochemicals and Reagents, Coagulation Proteins and Reagents, Enzyme Class Index, Plasma & Blood Pr
- {SNA} 3.4.x.x Peptidases, 3.x.x.x Hydrolases, Application Index, Coagulation Proteins and Reagents, Enzyme Class Index, Plasma & Blood Proteins, Plasmin, Proteolytic Enzymes, Proteolytic Enzymes and Substrates, Related Products, Selective Proteolytic Enzymes, Serum Proteins and Related Enzymes, Serum Related Enzymes, Streptokinase, Therapeutic Enzymes, 生化试剂, 蛋白质及衍生物, 酶、抑制剂和底物
相关文献及参考
- Bull. Wld. Hlth. Org. 33 , 235, (1965)
- Hacke W, Ringleb P, Stingele R., Update in thrombolytic therapy. Rev. Neurol. (Paris) 155 , 662-665, (1999)
- Bouros D, Schiza S, Siafakas N, Fibrinolytics in the treatment of parapneumonic effusions. Monaldi Arch. Chest Dis. 54 , 258-263, (1999)
- Barletta JF., Streptokinase and urokinase for the treatment of pleural effusions and empyemas. Pharmacotherapy 33 , 495-498, (1999) 摘要
- Merck 14 ,8825
安全信息
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Human - man DOSE/DURATION : 562500 iu/kg TOXIC EFFECTS : Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - dyspnea REFERENCE : JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 252,1314,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FOHEAW Folia Haematologica (Leipzig). (Buchexport, Postfach 160, Leipzig DDR-7010, Ger. Dem. Rep.) V.32- 1926- Volume(issue)/page/year: 103,445,1976
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Human DOSE/DURATION : 600 iu/kg TOXIC EFFECTS : Immunological Including Allergic - uncharacterized REFERENCE : JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 252,1314,1984
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FOHEAW Folia Haematologica (Leipzig). (Buchexport, Postfach 160, Leipzig DDR-7010, Ger. Dem. Rep.) V.32- 1926- Volume(issue)/page/year: 103,445,1976
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