15-O-Acetyl-4-deoxynivalenol from Fusarium graminearum 15-O-乙酰脱氧瓜萎镰菌醇 来源于禾谷镰刀菌
CAS 88337-96-6 MFCD00083218
化学结构图
SMILES: C[C@@]12C[C@@H](O)[C@@H](O[C@@H]3C=C(C)C(=O)[C@@H](O)[C@]13COC(C)=O)[C@]12CO1
化学属性
| Mol. Formula | C17 |
|---|---|
| Mol. Weight | 338 |
别名和识别编码
| Chemical Name | 15-O-Acetyl-4-deoxynivalenol from Fusarium graminearum |
|---|---|
| CAS Number | 88337-96-6 |
| Synonym | 15-乙酰氧基-3alpha,7alpha-二羟基-12,13-环氧单端孢霉-9-烯-8-酮 15-ADON 15-AcDON 15-Acetylvomitoxin 15-Acetylvomitoxin 15-O-乙酰脱氧瓜萎镰菌醇 来源于禾谷镰刀菌 (3?,7?)-15-(Acetyloxy)-12,13-epoxy-3,7-dihydroxy-trichothec-9-en-8-one 15-O-Acetyl-4-deoxynivalenol Deoxynivalenol 15-Acetate 15-O-乙酰脱氧瓜萎镰菌醇 来源于禾谷镰刀菌 15-乙酰氧基-3α,7α-二羟基-12,13-环氧单端孢霉-9-烯-8-酮 15-乙酰脱氧瓜萎镰菌醇 溶液 15-乙酰脱氧瓜萎镰菌醇 15-Acetyldeoxynivalenol 15-乙酰氧基-3α,7α-二羟基-12,13-环氧单端孢霉-9-烯-8-酮 |
| MDL Number | MFCD00083218 |
| PubChem Substance ID | 24890561 |
| EC Number | 200-835-2 |
| Chemical Name Translation | 15-O-乙酰脱氧瓜萎镰菌醇 来源于禾谷镰刀菌 |
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分类
- {SA} A, AA to AL, Alphabetic, Analytical Standards, Analytical/Chromatography, Biotoxins, Chromatography,
- Analytical Standards, Analytical/Chromatography, Application CRMs, Biotoxins, CRM & Matrix RM, Certified Reference Materials (CRMs), Chromatography, Food and Agriculture CRM, Life Sciences Standards, Mycotoxins, Neat, Other
- {S
- {SNA} All alphabetically sorted, Analytical Standards, Biotoxin and Mycotoxin Standards, Food and Cosmetic Component Standards, Mycotoxins, Single component solutions, 分
产品应用
- A mycotoxin produced by the fungi Fusarium culmorum and Fusarium graminearum, inhibits protein synthesis.
相关文献及参考
- Ashraf, A.; et al.: Int. J. Biol. Biotechnol., 4, 391 (2007),
- Burlakoti, R., et al.: App. Environ. Microbiol., 74, 6513 (2008),
- Steinmetz, W., et al.: Eur. J. Med. Chem., 44, 4485 (2009),
- [1]. Juan-García A, et al. Binary and tertiary combination of alternariol, 3-acetyl-deoxynivalenol and 15-acetyl-deoxynivalenol on HepG2 cells: Toxic effects and evaluation of degradation products. Toxicol In Vitro. 2016 Aug;34:264-273.
安全信息
GHS Symbol
- P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P301+P310
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
- H331 Toxic if inhaled 吸入中毒
- H311 Toxic in contact with skin 皮肤接触中毒
- H300 Fatal if swallowed 吞食致命
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入，皮肤接触及吞食都有毒
- R11 Highly flammable 非常易燃
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- R36 Irritating to eyes 刺激眼睛
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- S16 Keep away from sources of ignition - No smoking 远离火源，禁止吸烟；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 113 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEMIDF Applied and Environmental Microbiology. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.31- 1976- Volume(issue)/page/year: 50,1304,1985
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 34 mg/kg TOXIC EFFECTS : Gastrointestinal - ulceration or bleeding from small intestine Kidney, Ureter, Bladder - inflammation, necrosis, or scarring of bladder Blood - changes in spleen REFERENCE : FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 25,155,1987
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