Morphinan-6-alpha-ol,7,8-didehydro-4,5-alpha-epoxy-3-ethoxy-17-methyl- Ethyl
CAS 76-58-4 MFCD00083327
化学结构图
SMILES: CCOc1ccc2c3c1O[C@H]1[C@@H](O)C=C[C@H]4[C@@H](C2)N(C)CC[C@]314
化学属性
| Mol. Formula | C19H23NO3 |
|---|---|
| Mol. Weight | 313.43 |
别名和识别编码
| Chemical Name | Morphine |
|---|---|
| CAS Number | 76-58-4 |
| Synonym | 3-Ethoxymorphine (5?,6?)-7,8-Didehydro-4,5-epoxy-3-ethoxy-17-methylmorphinan-6-ol Ethylmorphine 3-O-Ethylmorphine Codethyline Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-ethoxy-17-methyl-, Diohin Dionine |
| MDL Number | MFCD00083327 |
| PubChem Substance ID | 5359271 |
| EC Number | 200-970-7 |
| Wiswesser Line Notation | T B6566 B6/CO 4ABBC R BX HO PN DU GHT&&TTJ FQ JO2 P1 |
| Chemical Name Translation | Ethyl |
| InChI | InChI=1S/C19H23NO3/c1-3-22-15-7-4-11-10-13-12-5-6-14(21)18-19(12,8-9-20(13)2)16(11)17(15)23-18/h4-7,12-14,18,21H,3,8-10H2,1-2H3/t12-,13+,14-,18-,19-/m0/s1 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- Aromatics
- Chiral Reagents
- Pharmaceuticals
- Intermediates & Fine Chemicals,
- {SA} Alkaloids, Alphabetic, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Chemical Structure, Chromatography, Drugs & Metabolites, Drugs of Abuse, E, EQ - EZ, Excitatory Amino Acids - Opiod Agonists, Forensic and Veterinary Standards, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Morphine, Neat Compounds, Neurobiology, Neuroscience, Opioid Agonists,
- {SN
产品应用
- Analgesic (narcotic); antitussive. Mydriatic.
相关文献及参考
- Ertl, P., et al.: J. Med. Chem., 43, 3714
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- R22 Harmful if swallowed 吞咽有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 62 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 25,929,1973
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 520 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 21,719,1971
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 120 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 8,261,1950
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 110 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 31,655,1976
TYPE OF TEST : LD50
京ICP备2020036287号