Arsenic 砷

CAS 7440-38-2 MFCD00085309

化学结构图

7440-38-2
SMILES: [As]

化学属性

Mol. FormulaAs
Mol. Weight75
Boiling Point613°C
Density1.0
Melting Point817°C
TSCAYes
Solubilityinsoluble
Appearance powder
Stability对湿度敏感

别名和识别编码

Chemical NameArsenic
CAS Number7440-38-2
PubChem Substance ID5359596
EC Number231-148-6
MDL NumberMFCD00085309
Synonym Arsenic-75 砷标准溶液 Arsenicals 砷标样 灰砷 Metallic arsenic Grey arsenic Arsenic Arsenic Black Arsen Colloidal arsenic 高纯砷 砷
Chemical Name Translation
Merck Number13,802
Wiswesser Line NotationAS4
LabNetwork Molecule IDLN00193415
InChIInChI=1S/As
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分类

  • {SNA} Arsenic, As, Materials Science, Metal and Ceramic Science, Metals, Ultra-High Purity Materials
  • {Chemicalbook} 无机化工产品: 无机盐: Cu单质
  • {SA} Arsenic, Materials Science, Metal and Ceramic Science, Metals

产品应用

  • 用于ICP-AES、AAS、AFS、ICP-MS、离子色谱等。滴定分析用标准溶液。校准仪器和装置;评价方法;工作标准;质量保证/质量控制;其他。

相关文献及参考

  • Merck: 14,794

安全信息

GHS Symbol
WGK Germany3
Hazard Codes T,N
Hazard statements
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H331 Toxic if inhaled 吸入中毒
  • H301 Toxic if swallowed 吞食有毒
  • H301+H331
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
RTECSCG0525000
Precautionary statements
  • P301+P310
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
Signal word Danger
Safety Statements
  • S20/21 When using do not eat, drink or smoke 使用时,不得进食,饮水或吸烟;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S53 Avoid exposure - obtain special instructions before use 避免接触,使用前获得特别指示说明;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
Packing GroupII
UN Number UN 1558 6.1/PG 2 UN3264 UN1558
Risk Statements
  • R52/53
  • R34 Causes burns 会导致灼伤
  • R23/25 Toxic by inhalation and if swallowed 吸入及吞食都有毒
  • R50/53
  • R45 May cause cancer 可能致癌
  • R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
  • R22 Harmful if swallowed 吞咽有害
Hazard Class6.1
Storage condition Air Sensitive
Warnings 危化品目录(2015) 危险化学品
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 76 mg/kg/12Y-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Blood - hemorrhage
REFERENCE :
   RMCHAW Revista Medica de Chile.  (Sociedad Medica de Santiago, Esmeralda
   678, Casilla 23-d, Santiago, Chile)  V.1-    1872- Volume(issue)/page/year:
   99,664,1971

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   52,425,1942

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13390 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 64,191,1990

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 7857 mg/kg/55Y
TOXIC EFFECTS :
   Gastrointestinal - changes in structure or function of esophagus
   Blood - hemorrhage
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   CMAJAX Canadian Medical Association Journal.  (Canadian Medical Assoc., POB
   8650, Ottawa, ON K1G 0G8, Canada)  V.1-    1911-  Volume(issue)/page/year:
   120,168,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 46200 ug/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 3

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 763 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Unreported
TEST SYSTEM             : Human
DOSE/DURATION           : 4286 ug/kg
REFERENCE :
   HUGEDQ Human Genetics.  (Springer-Verlag New York, Inc., Service Center, 44
   Hartz Way, Secaucus, NJ 07094)  V.31-    1976-  Volume(issue)/page/year:
   48,1,1979

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 280 mg/kg/8W
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 113,293,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 605 ug/kg
SEX/DURATION            : female 35 week(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 42(8),30,1977

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 580 ug/kg
SEX/DURATION            : female 30 week(s) pre-mating
                          female 1-20 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 41,620,1978

其他信息

  • 爆炸物危险特性:粉尘近火可以爆炸; 遇氧化物接触反应激烈
  • 用途二:用于半导体材料、光学材料等
  • 下游产品:苯甲酸 --> 甲基氧化胂 --> 砷铜合金 --> 三氯化砷(氯化亚砷) --> 砷铅合金 --> 砷化锌 --> 砷化铟 --> 碘化砷
  • 职业标准:TWA 0.01 毫克 (砷)/立方米
  • F:10
  • 可燃性危险特性:粉尘可燃; 燃烧产生有毒砷化物烟雾; 接触酸产生有毒烟雾
  • 灭火剂:干粉,泡沫,沙土,二氧化碳, 雾状水
  • 类别:有毒物品
  • 外观性质:银灰色发亮的块状固体,质硬而脆。
  • 砷在干燥空气中稳定,在潮湿空气中生成黑色氧化膜;砷与水、碱和非氧化酸不起作用,不溶于水,溶于硝酸和王水,也能溶解于强碱,生成砷酸盐。能与硝酸、浓硫酸反应。单质砷在高温时能与许多非金属作用,所有金属的砷酸盐都有毒
  • 储运特性:库房通风低温干燥; 与食品原料和氧化剂分开存放
  • 用途五:用于制造硬质合金;黄铜中含有微量砷时可以防止脱锌;砷的化合物可用于杀虫及医疗。砷和它的可溶性化合物都有毒。高纯砷还用于半导体和激光技术中。
  • 不溶于水、碱液、多数有机溶剂,溶于硝酸、热碱液。
  • 毒性:参见三氧化二砷。
  • 参考质量标准:国家标准GB 3495—83 牌号 化学成分/ 砷≥ 杂质含量,≤ 锑 铋 硫 杂质总量 外观 呈银灰色金属块状,不应带有外来夹杂物。最小粒度不小于2mm As 99 0.4 0.1 0.3 1.0
  • Alfa Aesar:砷块,99.999%(metalsbasis) Arsenic lump, 99.999% (metals basis)(7440-38-2)
  • MOL 文件:7440-38-2.mol
  • 用途三:供合金制造和半导体等工业用。
  • 砷价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 53205361 砷 100ml 250元 2011/08/23 53205360 砷 100ml 250元 2010/06/21 195825000 砷 Arsenic standard solution , for AAS, 1 mg/ml As in 2% KOH 500 ML 1351元
  • 用途一:主要用于制硬质合金、玻璃、医药、颜料、农药等
  • Acros Organics:砷标准溶液 Arsenic standard solution, 1 mg/ml As in 2% KOH, for AAS(7440-38-2)
  • 急性毒性:口服-大鼠 LD50: 763 毫克/公斤; 口服-小鼠 LD50: 145 毫克/公斤
  • Sigma Aldrich:7440-38-2(sigmaaldrich)
  • 毒性分级:高毒
  • 用途四:用于制取合金的添加物、特种玻璃、涂料、医药及家药等。用于ICP-AES、AAS、AFS、ICP-MS、离子色谱等。滴定分析用标准溶液。校准仪器和装置;评价方法;工作标准;质量保证/质量控制;其他。
  • 方法一:气相还原法将备有气化段、反应段、析出段的三个电炉的装置组装起来。中央反应部分是内径为20~25mm的石英管,在其中装入经真空加热排掉气体的木炭,两端用石英棉堵住,在石英盘里放人三氧化二砷,放到气化段,以400~500 mI/min的速度通人经提纯的氮气。将气化段保持在400℃,反应段650℃,析出段350~400℃,经反应约1h,析出单质砷,再经蒸馏,制得砷成品。
  • MSDS 信息:砷(7440-38-2).msds
  • 上游原料:炭黑 --> 三氧化二砷 --> 石英管 --> 石英棉 --> 石英盘

系列性分类