• 原料直供
• 试剂商城
• 直接询价

分类

• Sulfur & Selenium Compounds
• Heterocycles
• {SNA} Building Blocks, Chemical Synthesis, Heterocyclic Building Blocks, Thiazolines/Thiazolidines
• Pharmaceuticals
• Intermediates & Fine Chemicals
• {SNA} Active Esters/Additives, Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling, Synthetic Reagents

产品应用

• 用于高选择性手性合成青霉烷和碳青霉烷类 β-内酰胺抗生素的工具。

相关文献及参考

• Reaction with ɑ-bromo esters gives the S-alkoxycarbonylmethyl derivatives, which can be C-alkylated by alkyl halides, using NaH as base. Sulfur-free products can be obtained by reduction (Zn/AcOH) to give the substituted acetic acid, or by reaction with iodidomethane to give the corresponding ɑ-iodo ester: Tetrahedron Lett., 2677 (1977).
• Thomes, J. et al.: Jap. J. Pharmacol., 58, 201 (1992); Buxeraud, J. et al.: Eur. J. Med. Chem., 20, 43 (1985); Cheng, J. et al.: Nongyao, 38, 12 (1999);
• Used in the chain-lengthening of alkyl halides by trans-iodopropenylenation: Org. Synth. Coll., 6, 704 (1988):

安全信息

GHS Symbol

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 97,478,1949

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 90,260,1947

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 710 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AECTCV Archives of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   070944)  V.1-    1973-  Volume(issue)/page/year: 14,111,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RAREAE Radiation Research.  (Academic Press, Inc., 1 E. First St., Duluth,
   MN 55802)  V.1-    1954-  Volume(issue)/page/year: 7,22,1957

其他信息

• TCI Shanghai:2-巯基噻唑啉 2-Mercaptothiazoline,>;98.0%(T)(96-53-7)
• 图谱信息:2-巯基噻唑啉(96-53-7)红外图谱(IR2) 2-巯基噻唑啉(96-53-7)红外图谱(IR1) 2-巯基噻唑啉(96-53-7)质谱(MS) 2-巯基噻唑啉(96-53-7)核磁图( 13 CNMR) 2-巯基噻唑啉(96-53-7)核磁图( 1 HNMR)
• MOL 文件:96-53-7.mol
• MSDS 信息:2-Mercaptothiazoline(96-53-7).msds
• 用途二:医药中间体。该品经水解得到半胱胺，是H2受体拮抗剂西咪替丁、雷尼替丁的中间体。
• Alfa Aesar:2-巯基噻唑啉,97% 2-Mercaptothiazoline, 97%(96-53-7)
• 海关编码:29341000
• 上游原料:乙醇胺
• Acros Organics:2-巯基噻唑啉 2-Mercaptothiazoline, 98%(96-53-7)
• 2-巯基噻唑啉价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 M0065 2-巯基噻唑啉 2-Mercaptothiazoline 25G 195元 2014/06/02 M0065 2-巯基噻唑啉 2-Mercaptothiazoline 500G 1300元 2010/06/21 125561000 2-巯基噻唑啉 2-Mercaptothiazoline 98% 100 GR 320元
• 下游产品:4-乙酰氧基氮杂环丁酮
• 用途一:酸性光亮镀铜添加剂，可获得良好光亮度与整平性，起光速度快
• Sigma Aldrich:96-53-7(sigmaaldrich)
• 检测方法:GC,NMR
• 方法一:乙醇胺以硫酸酯化，再与二硫化碳在氢氧化钠作用下环合而得。