Tyrphostin 25
CAS 118409-58-8 MFCD00133900
化学结构图
SMILES: N#CC(=CC1=CC(O)=C(O)C(O)=C1)C#N
化学属性
| Mol. Formula | C10H6N2O3 |
|---|---|
| Mol. Weight | 202.17 |
别名和识别编码
| Chemical Name | Tyrphostin 25 |
|---|---|
| CAS Number | 118409-58-8 |
| Synonym | ([3,4,5-Trihydroxybenzylidene]malononitrile) (3,4,5-Trihydroxybenzylidene)malononitrile |
| MDL Number | MFCD00133900 |
| PubChem Substance ID | 24278753 |
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分类
- Inhibitors; Tyrosine Kinase Inhibitors
- {SNA} Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Epidermal Growth Factor Receptor (EGFR), Kinase/Phosphatase Biology, P to Q, Protein Kinase Inhibitors, Protein kinase, tyrosine, EGF receptor, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors
产品应用
- An inhibitor of epidermal growth factor receptor tyrosine kinase activity and has a reported IC50 of 15 ?M for the autophosphorylation of the EGF-receptor.
相关文献及参考
- Gazit, A., et al.: J. Med. Chem., 32, 2344 (1989)
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