EPOPROSTENOL 依前列醇钠
CAS 61849-14-7 MFCD00135629
化学结构图
SMILES: [Na+].CC/C=C\C[C@H](O)/C=C/[C@@H]1[C@H]2C/C(=C\CCCC([O-])=O)/O[C@H]2C[C@H]1O
化学属性
| Mol. Formula | C20H31NaO5 |
|---|---|
| Mol. Weight | 374.45 |
别名和识别编码
| Chemical Name | Epoprostenol sodium |
|---|---|
| Synonym | (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt Epoprostenol 钠 PGI2-Na Prostacyclin sodium salt (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid sodium salt Epoprostenol 钠盐 PGI2-Na Prostacyclin sodium salt Epoprostenol 钠 Epoprostenol 钠盐 PGI2-Na Prostacyclin sodium salt |
| CAS Number | 61849-14-7 |
| PubChem Substance ID | 24898653 |
| EC Number | 263-273-7 |
| Beilstein Registry Number | 6472195 |
| MDL Number | MFCD00135629 |
| Chemical Name Translation | 依前列醇钠 |
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信息真实价格透明
资金保障
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分类
- {SNA} Arachidonic Acid Cascade, Eicosanoids (Prostaglandins, Leukotrienes), Fatty Acyls, Lipids in Cell Signaling, Prostaglandins, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 脂类
- {SNA} Biochemicals and Reagents, Eicosanoids (Prostaglandins, Leukotrienes), Fatty Acyls, Lipids,
相关文献及参考
- 1. Gryglewski, R.J., Prostacyclin among prostanoids Pharmacol. Rep. 60 , 3-11, (2008) 摘要
- Vane, J.R., Botting, R.M., Pharmacodynamic profile of prostacyclin. Am. J. Cardiol. 75 , 3, (1995) 摘要
- Moncada, S., et al., Relationship between prostacyclin and nitric oxide in the thrombotic process. Thromb. Res. 11 , 3-13, (1990) 摘要
- Salvemini, D., Regulation of cyclooxygenase enzymes by nitric oxide. Cell. Mol. Life Sci. 53 , 576, (1997) 摘要
- Dusting, G.J., et al., Nitric oxide in atherosclerosis: vascular protector or villain?. Clin. Exp. Pharmacol. Physiol. (Suppl.) 25 , S34-S41, (1998) 摘要
- Numaguchi, Y., Prostacyclin synthase gene transfer accelerates reendothelialization and inhibits neointimal formation in rat carotid arteries after balloon injury. Arterioscler. Thromb. Vasc. Biol. 19 , 727, (1999) 摘要
- Kroll, B., et al., Inhibition of transforming growth factor-β1 and UV light-induced apoptosis by prostanoids in primary cultures of rat hepatocytes. Toxicol. Appl. Pharmacol. 152 , 240, (1998) 摘要
- Taanman, J.W., et al., Measurement Of Kinetic Parameters Of Human Platelet DNA Polymerase Gamma. Methods 51 , 374-8, (2010) 摘要
- Safdar, Z., Treatment of pulmonary arterial hypertension: The role of prostacyclin and prostaglandin analogs (Epub ahead of print) Respir. Med. 105 , (2011)
- Merck 14 ,7875
安全信息
GHS Symbol
- H332 Harmful if inhaled 吸入有害
- H302 Harmful if swallowed 吞食有害
- H312 Harmful in contact with skin 皮肤接触有害
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- S22 Do not breathe dust 不要吸入粉尘；
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