N,N-Dimethylsphingosine

CAS 119567-63-4 MFCD00153960

化学结构图

119567-63-4
SMILES: CCCCCCCCCCCCC/C=C/[C@H](O)[C@@H](CO)N(C)C

化学属性

Mol. FormulaC20H41NO2
Mol. Weight327.545

别名和识别编码

Chemical NameN,N-Dimethylsphingosine
Synonym (2S,3R,4E)-2-(Dimethylamino)-4-octadecene-1,3-diol D-Erythro-N,N-Dimethylsphingosine DMS Dimethylsphingosine N,N-Dimethylsphingosine (2S,3R,4E)-2-(Dimethylamino)-4-octadecene-1,3-diol N,N-Dimethyl-D-erythro-sphingosine N,N-Dimethylsphingenine
CAS Number119567-63-4
MDL NumberMFCD00153960
Chemical Name Translation
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分类

  • Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Lipids in Cell Signaling, New Products, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, Sphingolipids, Sphingosine Kinase (SK)

相关文献及参考

  • Patti, G.J., et al., Metabolomics implicates alterd sphingolipids in chronic pain of neuropathic origin. Nature Chem. Biol. Jan. 22 , (2012)
  • Spijkers, L.J., et al., FTY720 (Fingolimod) increases vascular tone and blood pressure in spontaneously hypertenisve rats via inhibition of sphingosine kinase. Br. J. Pharmacol. Jan. 17 , (2012)
  • McDonald, R.A., et al., The sphingosine kinase inhibitor N,N-dimethylsphingosine inhibits neointimal hyperplasia. Br. J. Pharmacol. 159 , 543-553, (2010)

安全信息

WGK Germany1

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Serine/Threonine Kinase Biology - Kinase/Phosphatase Biology
  6. Serine/Threonine Kinase Inhibitors - Serine/Threonine Kinase Biology
  7. Sphingosine Kinase (SK) - Serine/Threonine Kinase Inhibitors

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