Calcium Ionophore A23187 mixed calcium magnesium salt 钙离子载体 A23187 混合钙镁盐

CAS N/A MFCD00213962

化学结构图

N/A
SMILES: C[C@@H]1CC[C@@]2(O[C@@H]1CC1=NC3C(=CC=CC=3O1)C(=O)O[Ca]OC(=O)C1=CC=CC3OC(C[C@H]4O[C@]5(CC[C@H]4C)O[C@H]([C@H](C)C(=O)C4=CC=CN4)[C@H](C)C[C@H]5C)=NC=31)O[C@H]([C@H](C)C(=O)C1=CC=CN1)[C@H](C)C[C@H]2C.C[C@@H]1CC[C@@]2(O[C@@H]1CC1=NC3C(=CC=CC=3O1)C(=O)O[Mg]OC(=O)C1=CC=CC3OC(C[C@H]4O[C@]5(CC[C@H]4C)O[C@H]([C@H](C)C(=O)C4=CC=CN4)[C@H](C)C[C@H]5C)=NC=31)O[C@H]([C@H](C)C(=O)C1=CC=CN1)[C@H](C)C[C@H]2C

化学属性

Mol. FormulaC29H37N3O6
Mol. Weight523.62

别名和识别编码

Chemical NameCalcium Ionophore A23187 mixed calcium magnesium salt
Synonym Calcimycin 钙离子载体 A23187 混合钙镁盐 Calcium Ionophore mixed calcium magnesium salt Calcium Ionophore A23187 mixed calcium magnesium salt Calcimycin Calcium Ionophore mixed calcium magnesium salt
MDL NumberMFCD00213962
PubChem Substance ID24892691
Chemical Name Translation钙离子载体 A23187 混合钙镁盐
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分类

  • {SNA} C, Stains & Dyes, A to Z, Stains and Dyes, 细胞生物学, 血液学和组织学
  • Biochemicals and Reagents, Chelators, Enzyme Inhibitors, Enzyme Inhibitors by Type, Enzymes, Inhibitors, and Substrates
  • {SNA} C, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes
  • {SNA} Chelators, Enzyme Inhibitors, Enzyme Inhibitors by Type, 生化试剂, 酶、抑制剂和底物

相关文献及参考

  • Pressman, B.C., et al., Biological applications of ionophores. Annu. Rev. Biochem. 45 , 50-530, (1976)
  • Kauffman, R.F., et al., Cation transport and specificity of ionomycin. Comparison with ionophore A23187 in rat liver mitochondria. J. Biol. Chem. 255 , 2735-2739, (1980) 摘要
  • Markram, H., and Segal, M., Calcimycin potentiates responses of rat hippocampal neurons to N-methyl-D-aspartate. Brain Res. 540 , 322-324, (1991) 摘要
  • Knowles, R.G., and Moncada, S., Nitric oxide as a signal in blood vessels. Trends Biochem. Sci. 17 , 399-402, (1992)

安全信息

WGK Germany3
Hazard Codes Xn
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
Signal word Warning

系列性分类

  1. Life Science 生命科学
  2. Hematology and Histology 血液学和组织学
  3. Stains and Dyes - Hematology and Histology
  4. Stains & Dyes, A to Z - Stains and Dyes
  5. C - Stains & Dyes, A to Z
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Enzymes, Inhibitors, and Substrates - Biochemicals and Reagents
  4. Enzyme Inhibitors - Enzymes, Inhibitors, and Substrates
  5. Enzyme Inhibitors by Type - Enzyme Inhibitors
  6. Chelators - Enzyme Inhibitors by Type

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