Dibenz[a,h]acridine 二苯并(A,H)杂蒽

CAS 226-36-8 MFCD00215935

化学结构图

226-36-8
SMILES: c1ccc2c(c1)ccc1nc3c(ccc4ccccc43)cc12

化学属性

Mol. FormulaC21H13N
Mol. Weight279.35

别名和识别编码

Chemical NameDibenz[a,h]acridine
CAS Number226-36-8
Synonym 1,2,5,6-Dibenzacridine 1,2,5,6-Dibenzoacridine 1,2,5,6-Dinaphthacridine 1,2:5,6-Dibenzacridine 7-Azadibenz(a,h)anthracene 7-Azadibenz[a,h]anthracene DB(a,h)AC Dibenz(a,d)acridine Dibenz[a,d]acridine dibenz(a,h)acridine dibenz(a,j)acridine dibenzacridine 二苯并[a,h]吖啶
MDL NumberMFCD00215935
Beilstein Registry Number0209261
Chemical Name Translation二苯并(A,H)杂蒽
Wiswesser Line NotationT G6 D6 B666 CNJ
LabNetwork Molecule IDLN01270440
PubChem Substance ID9183
InChIInChI=1S/C21H13N/c1-3-7-17-14(5-1)11-12-20-19(17)13-16-10-9-15-6-2-4-8-18(15)21(16)22-20/h1-13H
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分类

  • Aromatics
  • Metabolites & Impurities
  • Mutagenesis Research Chemicals
  • {SA} All PAH Standards, Alphabetic, Analytical Standards, Analytical/Chromatography, CRMs, Chromatography, D, DIA - DIC, Environmental Standards, PAHs, Volatiles/ Semivolatiles, neat
  • {SNA} All PAH Standards, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, CRMs, Chromatography, D, DIA - DIC, Environmental Standards, PAHs, Volatiles/ Semivolatiles, neat

产品应用

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相关文献及参考

  • Smith, C.J., et al.: Food Chem. Toxicol., 38, 637 (2000),
  • Koehler, D.A., et al.:; J. Ind. Ecol., 9, 143 (2005),

安全信息

Storage condition room temp
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1500 ug/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   20,97,1983

{hazar

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   20,97,1983

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 540 mg/kg/45W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of a

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 430 mg/kg/24W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   PRLBA4 Proceedings of the Royal Society of London, Series B: Biological
   Sciences.  (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76-

TYPE OF TEST            : TD - Toxic d

RTECSHN0875000
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intratracheal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 300 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 312,165,1994

TYPE OF TEST            : DNA adduct
ROUTE OF EXPOSURE       : Intratracheal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 75 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 312,165,1994

TYPE OF TEST            : Sister chromatid exchange
ROUTE OF EXPOSURE       : Intratracheal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 150 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 312,165,1994

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - rat Embryo
DOSE/DURATION           : 1 mg/L
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   51,799,1973

Hazard statements
  • H301 Toxic if swallowed 吞食有毒
  • H318 Causes serious eye damage 严重伤害眼睛
  • H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷
  • H350 May cause cancer 可能致癌
  • H351 Suspected of causing cancer 怀疑致癌
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P310
  • P301+P316
  • P305+P351+P338
  • P305+P354+P338
  • P308+P313
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P317
  • P318
  • P321 Specific treatment (see … on this label). 具体治疗(见本标签上的)。
  • P330 Rinse mouth. 漱口
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

系列性分类


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