7H-Dibenzo[c,g]carbazole 7H-二苯并[c,g]咔唑

CAS 194-59-2 MFCD00215941

化学结构图

194-59-2
SMILES: c1ccc2c(c1)ccc1[nH]c3ccc4ccccc4c3c12

化学属性

Mol. FormulaC20H13N
Mol. Weight267.32
Melting Point152-154°C
Boiling Point400.51 °C at 760 mmHg

别名和识别编码

Chemical Name7H-Dibenzo[c,g]carbazole
CAS Number194-59-2
Synonym 7H-Dibenzo[c,g]carbazole {LY} 7H-Dibenzo[c,g]carbazole {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 7H-Dibenzo[c,g]carbazole {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL NumberMFCD00215941
PubChem Substance ID9134
Beilstein Registry Number213015
Chemical Name Translation7H-二苯并[c,g]咔唑
EC Number205-895-3
Reaxys-RN213015
Wiswesser Line NotationT D6 C6 B566 MMJ
LabNetwork Molecule IDLN01270699
InChIInChI=1S/C20H13N/c1-3-7-15-13(5-1)9-11-17-19(15)20-16-8-4-2-6-14(16)10-12-18(20)21-17/h1-12,21H
Canonical SMILESC12=C(C3=CC=CC=C3C=C2)C(C4=CC=CC=C4C=C5)=C5N1
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Aromatics
  • Mutagenesis Research Chemicals
  • {SNA} All PAH Standards, Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, CRMs, Chromatography, D, DIA - DIC, Environmental Standards, PAHs, Volatiles/ Semivolatiles, neat

产品应用

  • A heterocyclic aromatic compound with potent mutagenic and carcinogenic properties.

相关文献及参考

  • Dowty, H., et al.: Carcinogenesis, 21, 991 (2000),

安全信息

Packing GroupIII
Storage condition 2-8°C, protect from light, stored under nitrogen {LY} 2-8°C, protect from light, stored under nitrogen {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitrogen {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C, protect from light, stored under nitr
Hazard Class6.1(b)
UN Number 2811
RTECSHO5600000
Signal word
GHS Symbol
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H350 May cause cancer 可能致癌
  • H351 Suspected of causing cancer 怀疑致癌
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P301+P317
  • P302+P352
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P308+P313
  • P313 Get medical advice/attention. 获取医疗咨询/就医
  • P318
  • P330 Rinse mouth. 漱口
  • P332 IF SKIN irritation occurs: 如果发生皮肤刺激:
  • P332+P313
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
  • P362+P364
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg/23W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Skin and Appendages - tumors
REFERENCE :
   PRLBA4 Proceedings of the Royal Society of London, Series B: Biological
   Sciences.  (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 
     1905-  Volume(issue)/page/year: 122,429,1937

{haz

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 280 mg/kg/32W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
   Liver - tumors
REFERENCE :
   BJCAAI British Journal of Cancer.  (Macmillan Press Ltd., Houndmills,
   Basingstoke, Hants. RG21 2XS, UK)  V.1-    1947-  Volume(issue)/page/year:
   4,203,19

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Implant
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 65 mg/kg/52W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Kidney, Ureter, Bladder - tumors
REFERENCE :
   JPBAA7 Journal of Pathology and Bacteriology.  (London, UK)  V.1-96,
   1892-1968.  For publisher information, see JPTLAS. Volume(issue)/page/year:
   68,561,1954

{ha

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   BIJOAK Biochemical Journal.  (Biochemical Soc. Book Depot, POB 32, Commerce
   Way,

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Liver - other changes
REFERENCE :
   BIJOAK Biochemical Journal.  (Biochemical Soc. Book Depot, POB 32, Commerce
   Way, Colchester, Essex CO2 8HP, UK)  V.1-    1906- Volume(issue)/page/year:
   32,1460,1938

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 10 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,4706,1986

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 1400 nmol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,4706,1986

{

TYPE OF TEST            : DNA adduct
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 37 umol/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 8,591,1987

TYPE OF TEST            : DNA adduct
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 80 umol/kg
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   49,2633,1989

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 20 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-

TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 500 nmol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,4706,1986

其他信息

  • Sigma Aldrich:194-59-2(sigmaaldrich)
  • MOL 文件:194-59-2.mol
  • 上游原料:乙酸 --> 无水醋酸钠 --> 四氯苯醌 --> beta-四氢萘酮 --> 2-萘肼盐酸盐

系列性分类


相关产品推荐