8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino-[3,2,1-jk]carbazole hydrochloride

CAS 16154-78-2 MFCD00220370

化学结构图

16154-78-2
SMILES: Cl.CC1=CC=C2C(=C1)C1CCCC3NCCN2C=13

化学属性

Mol. Weight262.81
Mol. FormulaC15H18N2.ClH

别名和识别编码

Chemical Name1H-Pyrazino(3,2,1-jk)carbazole,2,3,3a,4,5,6-hexahydro-8-methyl-, monohydrochloride
Alfabeta NameMETHYLHEXAHYDROPYRAZINOJKCARBAZOLEHYDROCHLORIDE AH82334561321[]-------,,,,,,,
MDL NumberMFCD00220370
CAS Number16154-78-2
Wiswesser Line NotationT C6566 1A P BN NM&&TTJ F1 &GH
Synonym 2,3,3a,4,5,6-Hexahydro-8-methyl-1H-pyrazino(3,2,1j,k)carbazole
Chemical Name Translation
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安全信息

Warnings IRRITANT
RTECSUQ3930000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 18,94,1984

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 67 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - tremor
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 38,5,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 185 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOVEFN Toksikologicheskii Vestnik.  (18-20 Vadkovskii per.  Moscow, 101479,
   Russia) History Unknown  Volume(issue)/page/year: (3),17,1993

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2060 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TOVEFN Toksikologicheskii Vestnik.  (18-20 Vadkovskii per.  Moscow, 101479,
   Russia) History Unknown  Volume(issue)/page/year: (3),17,1993

TYPE OF TEST            : LD50 - Lethal dose, 50 perce

系列性分类


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