5-Chloro-1-methyl-4-nitroimidazole, 99.5%, reference material 5-氯-1-甲基-4-硝基咪唑

CAS 4897-25-0 MFCD00233664

化学结构图

4897-25-0
SMILES: Cn1cnc([N+](=O)[O-])c1Cl

化学属性

Mol. FormulaC4H4ClN3O2
Mol. Weight161.55
Density1.422
Melting Point148-150 °C
Appearance 白色结晶性粉末。
Boiling Point362.3±22.0 °C at 760 mmHg

别名和识别编码

Chemical Name5-Chloro-1-methyl-4-nitroimidazole, 99.5%, reference material
CAS Number4897-25-0
Alfabeta NameCHLOROMETHYLNITROIMIDAZOLE H5141-------
MDL NumberMFCD00233664
Synonym 5-Chloro-1-methyl-4-nitroimidazole {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Chloro-1-methyl-4-nitroimidazole {} {} {} {} {} {} {} {} {} {}
EC Number225-521-2
Beilstein Registry Number23(5)4,493
PubChem Substance ID21010
Reaxys-RN136775
Chemical Name Translation5-氯-1-甲基-4-硝基咪唑
Wiswesser Line NotationT5N CNJ A1 DNW EG
LabNetwork Molecule IDLN00162214
InChIInChI=1S/C4H4ClN3O2/c1-7-2-6-4(3(7)5)8(9)10/h2H,1H3
Canonical SMILESO=[N+](C1=C(Cl)N(C)C=N1)[O-]
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信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • {SNA} Building Blocks, C3 to C8, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Imidazoles
  • Heterocycles,

安全信息

Warnings IRRITANT
Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P362+P364
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P405 Store locked up. 上锁保管。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P403+P233
  • P337+P317
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P352
  • P304+P340
  • P319
  • P305+P351+P338
  • P332+P317
  • P264+P265
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
RTECSNI4397100
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xi 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 10 umol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,1,1978

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • 用途二:医药中间体。与6-巯基嘌呤缩合可得到抗肿瘤药硫唑嘌呤。
  • 5-氯-1-甲基-4-硝基咪唑价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 C1646 5-氯-1-甲基-4-硝基咪唑 5-Chloro-1-methyl-4-nitroimidazole 5G 550元
  • 用途一:用于有机合成，是抗肿瘤药硫唑嘌呤的重要中间体
  • Acros Organics:5-氯-1-甲基-4-硝基咪唑 5-Chloro-1-methyl-4-nitroimidazole, 98%(4897-25-0)
  • TCI Shanghai:5-氯-1-甲基-4-硝基咪唑 5-Chloro-1-methyl-4-nitroimidazole,>;96.0%(N)(4897-25-0)
  • 方法一:由1-甲基-5-氯咪唑经硝化得到。将1-甲基-5-氯咪唑加入搪玻璃反应锅，然后在冷却下加入硝酸。继续在冷却下滴加硫酸，加毕，在100℃反应2h，再冷却，加入冰水析出产品，经过滤干燥得5-氯-1-甲基-4-硝基咪唑。收率为86%。
  • Sigma Aldrich:4897-25-0(sigmaaldrich)
  • MOL 文件:4897-25-0.mol
  • 上游原料:三氯氧磷 --> 五氯化磷 --> 硝酸钾 --> 搪玻璃反应锅 --> 5-氯-1-甲基咪唑 --> N,N'-二甲基草酰胺
  • 图谱信息:5-氯-1-甲基-4-硝基咪唑(4897-25-0)质谱(MS)
  • MSDS 信息:5-Chloro-1-methyl-4-nitro-1H-imidazole(4897-25-0).msds
  • 下游产品:硫唑嘌呤

系列性分类

  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Imidazoles 咪唑
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Halogenated Heterocycles 卤代杂环
  5. Imidazoles - Halogenated Heterocycles

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