CAS 636-26-0 MFCD00009777-4(1H)-Pyrimidinone,2,3-dihydro-5-methyl-2-thioxo- 4-羟基-2-巯基-5-甲基嘧啶 -LabNovo

4(1H)-Pyrimidinone,2,3-dihydro-5-methyl-2-thioxo- 4-羟基-2-巯基-5-甲基嘧啶

CAS 636-26-0 MFCD00009777

化学结构图

SMILES: Cc1c[nH]c(=S)[nH]c1=O

化学属性

Mol. Formula	C5H6N2OS
Mol. Weight	142.18
Melting Point	283-286°C
TSCA	Yes
Density	1.36
Appearance	乙酰乙酸乙酯与硫脲、无水碳酸钠反应得到甲基硫氧嘧啶（收率65.5%），这是一种具有苦杏仁味的结晶物，用于生产长效冠状动脉扩张药潘生丁。

别名和识别编码

Chemical Name	4(1H)-Pyrimidinone,2,3-dihydro-5-methyl-2-thioxo-
MDL Number	MFCD00009777
CAS Number	636-26-0
Synonym	5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {} {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {} {} {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {} {} {} {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {} {} {} {} {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one {} {} {} {} {} {} {} {} {} {} {} {} {LY} 5-Methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)
Beilstein Registry Number	120488
Reaxys-RN	120488
PubChem Substance ID	720471
Chemical Name Translation	4-羟基-2-巯基-5-甲基嘧啶
InChIKey	ZLAQATDNGLKIEV-UHFFFAOYSA-N
LabNetwork Molecule ID	LN00010231
InChI	InChI=1S/C5H6N2OS/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)
Canonical SMILES	O=C(C(C)=CN1)NC1=S

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

安全信息

GHS Symbol

WGK Germany3

Precautionary statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H335 May cause respiratory irritation 可能导致呼吸道刺激

RTECSXP2108500

Signal word Warning

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves

Safety Statements

S22 Do not breathe dust 不要吸入粉尘；
S36 Wear suitable protective clothing 穿戴适当的防护服；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

Risk Statements

R22 Harmful if swallowed 吞咽有害

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 97,478,1949

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 97,478,1949

Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

上游原料:乙醇 --> 盐酸 --> 甲醇 --> 乙醚 --> 乙酸 --> 钠 --> 甲苯 --> 硫酸钠 --> 丙酮 --> 碳酸氢钠 --> 原甲酸三乙酯 --> 硫脲 --> 锌粉 --> 碘 --> 2-溴乙酸乙酯
用途一:为抗甲状腺药
图谱信息:4-羟基-2-巯基-5-甲基嘧啶(636-26-0)核磁图( 1 HNMR) 4-羟基-2-巯基-5-甲基嘧啶(636-26-0)红外图谱(IR1) 4-羟基-2-巯基-5-甲基嘧啶(636-26-0)质谱(MS) 4-羟基-2-巯基-5-甲基嘧啶(636-26-0)核磁图( 13 CNMR) 4-羟基-2-巯基-5-甲基嘧啶(636-26-0)红外图谱(IR2)
TCI Shanghai:5-甲基-2-硫尿嘧啶 5-Methyl-2-thiouracil,>;98.0%(T)(636-26-0)
MOL 文件:636-26-0.mol
Sigma Aldrich:636-26-0(sigmaaldrich)
4-羟基-2-巯基-5-甲基嘧啶价格(试剂级):更新日期产品编号产品名称包装价格 2014/06/02 M0994 5-甲基-2-硫尿嘧啶 5-Methyl-2-thiouracil 25G 1980元 2014/06/02 M0994 5-甲基-2-硫尿嘧啶 5-Methyl-2-thiouracil 10G 999元 2010/05/25 L11983 4-羟基-2-巯基-5-甲基嘧啶, 98% 5-Methyl-2-thiouracil, 98% 50g 1484元
Alfa Aesar:4-羟基-2-巯基-5-甲基嘧啶,98% 5-Methyl-2-thiouracil, 98%(636-26-0)