ST638

CAS 107761-24-0 MFCD00236446

化学结构图

107761-24-0
SMILES: CCOC1C=C(/C=C(/C#N)\C(N)=O)C=C(CSC2C=CC=CC=2)C=1O

化学属性

Mol. FormulaC19H18N2O3S
Mol. Weight354.42
Melting Point134-135.5 °C

别名和识别编码

Chemical NameST638
Synonym α-Cyano-(3-ethoxy-4-hydroxy-5-phenylthiomethyl)cinnamide 2-Cyano-3-(3-ethoxy-4-hydroxy-5-((phenylthio)methyl)phenyl)-2-propenamide ST 638 ST638 alpha-Cyano-3-ethoxy-4-hydroxy-5-(phenylthiomethyl)cinnamide α-Cyano-(3-ethoxy-4-hydroxy-5-phenylthiomethyl)cinnamide
MDL NumberMFCD00236446
CAS Number107761-24-0
Beilstein Registry Number5634581
PubChem Substance ID329824465
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, Vascular Endothelial Growth Factor Receptor (VEGFR)
  • {SNA} Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, S, Vascular Endothelial Growth Factor Receptor (VEGFR), 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, Vascular Endothelial Growth Factor Receptor (VEGFR)

相关文献及参考

  • Watanabe, T., et al. , Inhibitors for protein-tyrosine kinases, ST638 and genistein: induce differentiation of mouse erythroleukemia cells in a synergistic manner. Exp. Cell Res. 183 , 335-342 , (1989)

安全信息

GHS Symbol
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
Hazard statements
  • H302 Harmful if swallowed 吞食有害
WGK Germany3
RTECSUC6316200 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #93-00938

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #93-00938

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Receptor Tyrosine Kinase Biology - Kinase/Phosphatase Biology
  6. Receptor Tyrosine Kinase Inhibitors - Receptor Tyrosine Kinase Biology
  7. Vascular Endothelial Growth Factor Receptor (VEGFR) - Receptor Tyrosine Kinase Inhibitors
  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Kinase/Phosphatase Biology - Cell Signaling and Neuroscience
  5. Receptor Tyrosine Kinase Biology - Kinase/Phosphatase Biology
  6. Receptor Tyrosine Kinase Inhibitors - Receptor Tyrosine Kinase Biology
  7. Vascular Endothelial Growth Factor Receptor (VEGFR) - Receptor Tyrosine Kinase Inhibitors

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