Flurogestone Acetate 氟孕酮醋酸酯

CAS 2529-45-5 MFCD00243094

化学结构图

2529-45-5
SMILES: CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C

化学属性

Mol. FormulaC23H31FO5
Mol. Weight406.49
Melting Point266-269 °C
Boiling Point526.7±50.0 °C at 760 mmHg

别名和识别编码

Chemical NameFlurogestone acetate
CAS Number2529-45-5
Synonym Fluorogestone acetate {PubChem} Flugestone Acetate Fluorogestone Acetate Flurogestone Flurogestone Acetate beta-Acetoxy-9-fluoro-11 beta-hydroxyprogesterone, 17 beta-hydroxyprogesterone, 17 beta-Acetoxy-9-fluoro-11 {} {PubChem} Flugestone {} {} {PubChem} Cronolone {} {} {} {} {} {} {PubChem} Acetate, Flurogestone {} {} {} {} {PubChem} Acetate, Fluorogestone {} {} {} {} {} {PubChem} Acetate, Flugestone {} {} {} {} {} {} {PubChem} 17 beta-Acetoxy-9-fluoro-11 beta-hydroxyprogesterone {} {} {} {} {} {} {} {PubChem} 17 beta Acetoxy 9 fluoro 11 beta hydroxyprogesterone {} {} {} {} {} {} {} {} {} {LY} Fluorogestone acetate {} {} {} {} {} {} {} {} {} {} {LY} Fluorogestone acetate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Fluorogestone acetate {} {} {} {} {} {} {} {} {} {} {} {} {LY} Fluorogestone acetate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
EC Number219-776-9
Chemical Name Translation氟孕酮醋酸酯
Wiswesser Line NotationL E5 B666 OV MUTJ A1 BF CQ E1 FV1 FOV1
Beilstein Registry Number3123549
PubChem Substance ID10476437
InChIInChI=1S/C23H31FO5/c1-13(25)22(29-14(2)26)10-8-17-18-6-5-15-11-16(27)7-9-20(15,3)23(18,24)19(28)12-21(17,22)4/h11,17-19,28H,5-10,12H2,1-4H3/t17-,18-,19-,20-,21-,22-,23-/m0/s1
Canonical SMILESCC(O[C@@]1(CC[C@]2([C@@]3(CCC4=CC(CC[C@@]4([C@]3([C@H](C[C@]12C)O)F)C)=O)[H])[H])C(C)=O)=O
MDL NumberMFCD00243094
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids

产品应用

  • A synthetic progesterone, used to induce oestrus synchronisation in goats and sheep.

相关文献及参考

  • Mei, C., et al.: Reproduct. Dom. An., 44, 735 (2009),
  • Letelier, C., et al.: Theriogenol., 71 676 (2009),

安全信息

RTECSTU5024000
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravaginal
SPECIES OBSERVED        : Mammal - domestic
DOSE                    : 158 ug/kg
SEX/DURATION            : female 19 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
   Reproductive - Fertility - other measures of fertility
   Reproductive - Effects on Newborn - other neonatal measures or effects
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 22,515,1970

Hazard statements
  • H351 Suspected of causing cancer 怀疑致癌
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
  • H373 May causes damage to organs through prolonged or repeated exposure 长期或频繁接触可能会损伤器官
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前,切勿操作。
  • P203
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P308+P313
  • P318
  • P319
  • P391 Collect spillage. Hazardous to the aquatic environment 收集对水环境有危害的泄漏物。
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Storage condition Store at room temperature {LY} Store at room temperature {} {LY} Store at room temperature {} {} {LY} Store at room temperature {} {} {} {LY} Store at room temperature {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Store at room temperature {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

系列性分类


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