(R)-2,3-Dihydroxypropyl 4-methylbenzenesulfonate (R)-对甲苯磺酸-1-甘油酯
CAS 41274-09-3 MFCD00270084
化学结构图
SMILES: CC1=CC=C(C=C1)S(=O)(=O)OC[C@H](O)CO
化学属性
| Mol. Formula | C10H14O5S |
|---|---|
| Mol. Weight | 246.28 |
别名和识别编码
| Chemical Name | (R)-2,3-Dihydroxypropyl 4-methylbenzenesulfonate |
|---|---|
| CAS Number | 41274-09-3 |
| Synonym | (R)-1-Tosyloxyglycerol (R)-2,3-二羟基丙基对甲苯磺酸酯 (R)-3-甲苯磺酰氧基-1,2-丙二醇 sn-甘油基 1-(对甲苯磺酸酯) (R)-3-(Tosyloxy)-1,2-propanediol (R)-对甲苯磺酸-1-甘油酯 (R)-1,2,3-Propanetriol 4-methylbenzenesulfonate (R)-3-(p-Toluenesulfonyloxy)-1,2-propanediol |
| MDL Number | MFCD00270084 |
| Chemical Name Translation | (R)-对甲苯磺酸-1-甘油酯 |
| PubChem Substance ID | 329799902 |
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分类
- Sulfur & Selenium Compounds
- Chiral Reagents
- Aromatics
- {SNA} Alcohols, Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Organic Building Blocks
产品应用
- A chiral synthon for general asymmetric synthesis. An intermediate for the synthesis of chiral aryloxypropanolamines, which make up the majority of known potent beta-adrenergic blockers.
相关文献及参考
- Fuji, M., et al.: Chem. Pharm. Bull., 40, 2353 (1992),
- Meerpoel, L., et al.: J. Med. Chem., 48, 2184 (2005),
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
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