N-Benzoyl-(2R,3S)-3-Phenylisoserine N-苯甲酰-(2R,3S)-3-苯基异丝胺酸

CAS 132201-33-3 MFCD00274633

化学结构图

132201-33-3
SMILES: OC(=O)[C@H](O)[C@@H](NC(=O)C1C=CC=CC=1)C1C=CC=CC=1

化学属性

Mol. FormulaC6H5CONHCH(C6H5)CH(OH)CO2H
Mol. Weight285.29
Melting Point169-172 °C (lit.)

别名和识别编码

Chemical NameN-Benzoyl-(2R,3S)-3-Phenylisoserine
CAS Number132201-33-3
Synonym (?R,?S)-?-(Benzoylamino)-?-hydroxybenzenepropanoic Acid (2R,3S)-N-Benzoyl-3-phe [R-(R*,S*)]-?-(benzoylamino)-?-hydroxybenzenepropanoic Acid (2R,3S)-3-(Benzoylamino)-2-hydroxy-3-phenylpropionic Acid N-苯甲酰基-(2R,3S)-3-苯基异丝氨酸
MDL NumberMFCD00274633
PubChem Substance ID24868119
Chemical Name TranslationN-苯甲酰-(2R,3S)-3-苯基异丝胺酸
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分类

  • Anti-virals
  • Amino Acids & Derivatives
  • {SA} Chemical Biology, Chemical Synthesis, Peptide Chemistry, Serine Derivatives, Unnatural Amino Acid Derivatives
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Aromatics
  • {SNA} Chemical Biology, Chemical Synthesis, Peptide Chemistry, Serine Derivatives, Unnatural Amino Acids & Derivatives

产品应用

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相关文献及参考

  • Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);
  • 1. Kingston, D.G.I. et al. J. Nat. Prod. 53 , 1, (1990)
  • 2. Mangatal, L. et al. Tetrahedron 45 , 4177, (1989)
  • 3. Borman, S. Chem. Eng. News 69(35) , 11, (1991)
  • 4. Rowinsky, E. Donehower, R. J. Natl. Cancer Inst. 83 , 1778, (1991) 摘要
  • 5. Rowinsky, E. et al. J. Clin. Oncol. 9 , 1692, (1991) 摘要
  • 6. Ojima, I. et al. Tetrahedron 48 , 6985, (1992)
  • 7. Ojima, I. et al. Tetrahedron Lett. 34 , 4149, (1993)
  • 8. Holton, R.A. et al. J. Am. Chem. Soc. 116 , 1597, (1994)
  • FT-IR 2 (2), 3015:A

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Signal word Warning
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Serine Derivatives - Unnatural Amino Acid Derivatives
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Serine Derivatives - Unnatural Amino Acid Derivatives
  1. Functional Group 官能团索引
  2. alpha-hydroxyacid

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