Furagin 呋喃烯啶

CAS 1672-88-4 MFCD00431319

化学结构图

1672-88-4
SMILES: O=C1CN(N=CC=Cc2ccc([N+](=O)[O-])o2)C(=O)N1

化学属性

Mol. FormulaC10H8N4O5
Mol. Weight264
SolubilityDMSO

别名和识别编码

Chemical NameFuragin
CAS Number1672-88-4
Synonym 1-((3-(5-Nitro-2-furyl)allylidene)amino)-hydantoin 1-((3-(5-Nitro-2-furyl)allylidene)amino)hydantoin; 1-[[(E)-3-(5-Nitrofuran-2-yl)prop-2-enylidene]amino]imidazolidine-2,4-dione 1-((3-(5-nitro-2-furanyl)-2-propenylidene)amino)-4-imidazolidinedione 1-((3-(5-nitro-2-furyl)allylidene)amino)-hydantoi 1-((3-(5-nitro-2-furyl)allylidene)amino)-hydantoin 1-((3-(5-硝基-2-呋喃基)烯丙亚基)氨基)海因 1-(3-(5-Nitro-2-furyl)-N-2-propenylidine)amino-hydantoin 1-(3-(5-nitro-2-furyl)-n-2-propenylidine)amino-hydantoin 1-(N-[1-Methyl-2-(5-nitropyr-2-yl)-ethyliden]amino]imidazolidine-2,4-dione 1-[[(E)-3-(5-Nitrofuran-2-yl)prop-2-enylidene]amino]imidazolidine-2,4-dione 1-[[3-(5-Nitro-2-furanyl)-2-propen-1-ylidene]amino]- 1-[[3-(5-Nitro-2-furanyl)-2-propenylidene]amino]-2,4-imidazolidinedione 2,4-Imidazolidinedione, 1-((3-(5-nitro-2-fu
MDL NumberMFCD00431319
Chemical Name Translation呋喃烯啶
Wiswesser Line NotationT5OJ BNW E1U2UN- AT5NVMV EHJ
Beilstein Registry Number0307076
LabNetwork Molecule IDLN00199036
PubChem Substance ID6870646
InChIInChI=1S/C10H8N4O5/c15-8-6-13(10(16)12-8)11-5-1-2-7-3-4-9(19-7)14(17)18/h1-5H,6H2,(H,12,15,16)/b2-1+,11-5+
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分类

  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Furagin (a nitrofurantoin analog) has the same efficacy in treating acute cystitis as Ciprofloxacin, however the duration of therapy is longer. Antibacterial.

相关文献及参考

  • Agace, W., et al.: J. Clin. Invest., 92, 780

安全信息

Storage condition 储存温度-20°C
RTECSMU3870000 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 50 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 26,3,1974

TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 3 mg/L
REFERENCE :
   CJMIAZ Canadian Journal of Microbiology.  (National Research Council of
   Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.1- 
     1954-  Volume(issue)/page/year: 10,932,1964

Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P264+P265
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P301+P317
  • P302+P352
  • P304+P340
  • P305+P351+P338
  • P312 Call a POISON CENTER or doctor/physician if you feel unwell. 如果你感觉不适，呼叫解毒中心或医生/医师。
  • P319
  • P321 Specific treatment (see … on this label). 具体治疗（见本标签上的）。
  • P330 Rinse mouth. 漱口
  • P332+P313
  • P332+P317
  • P337+P313
  • P337+P317
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
  • P362+P364
  • P403+P233
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

其他信息

  • MOL 文件:1672-88-4.mol

系列性分类

  1. Functional Group 官能团索引
  2. carboxylic acid imide, N-unsubstituted
  1. Functional Group 官能团索引
  2. semicarbazone

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