3,6-Bis(Dimethylamino)-10-Nonylacridin-10-Ium Bromide 3,6-双(二甲氨基)-10-壬基吖啶-10-鎓溴化物

CAS 75168-11-5 MFCD00467605

化学结构图

75168-11-5
SMILES: [Br-].CCCCCCCCC[N+]1C2C=C(C=CC=2C=C2C=CC(=CC=12)N(C)C)N(C)C

化学属性

Mol. FormulaC26H38BrN3
Mol. Weight473
Melting Point250

别名和识别编码

Chemical Name3,6-Bis(Dimethylamino)-10-Nonylacridin-10-Ium Bromide
Synonym 10-Nonylacridine orange bromide 10-Nonylacridine orange bromide 3,6-Bis(dimethylamino)-10-nonylacridinium bromide 10-壬基吖啶橙溴化物 3,6-Bis(dimethylamino)-10-nonylacridinium bromide
MDL NumberMFCD00467605
CAS Number75168-11-5
Chemical Name Translation3,6-双(二甲氨基)-10-壬基吖啶-10-鎓溴化物
PubChem Substance ID329770942
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分类

  • A, Alphabetical, Biochemicals and Reagents, Fluorescent Indicators and Probes, Fluorescent Probes, Labels, Particles and Stains, Hematology and Histology, Lipophilic and Membrane Probes, Stains & Dyes, A to Z, Stains and Dyes
  • {SNA} A, Alphabetical, Fluorescent Indicators and Probes, Lipophilic and Membrane Probes, Stains & Dyes, A to Z, Stains and Dyes, 生化试剂, 细胞生物学, 荧光探针，标记，粒子和染色剂, 血液学和组织学
  • {SNA} A, Alphabetical, Biochemicals and Reagents, Fluorescent Indicators and Probes, Fluorescent Probes, Labels, Particles and Stains, Hematology and Histology,

产品应用

  • 异染性染料，在活体细胞中用作线粒体荧光探针，对线粒体的定位研究。该染料也用来在流式细胞计上分析线粒体，了解多药物抗性，和小鼠胸腺细胞凋亡期间测量线粒体的变化。

相关文献及参考

  • Cossarizza, A., Mitochondrial modifications during rat thymocyte apoptosis: a study at the single cell level. Exp. Cell Res. 214 , 323, (1994)
  • Kessel, D., Characterization of multidrug resistance by fluorescent dyes. Cancer Res. 51 , 4665, (1991)

安全信息

GHS Symbol
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Storage condition 储存温度： 2-8°C
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S36 Wear suitable protective clothing 穿戴适当的防护服；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

其他信息

  • 溶于二甲基亚砜、乙醇和甲醇。

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Detection - Fluorescent Probes, Labels, Particles and Stains
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Acridines
  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Fluorescent Probes, Labels, Particles and Stains - Biochemicals and Reagents
  4. Fluorescent Indicators and Probes - Fluorescent Probes, Labels, Particles and Stains
  5. Lipophilic and Membrane Probes - Fluorescent Indicators and Probes
  6. Alphabetical - Lipophilic and Membrane Probes

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