N-(3-Chloro-4-(4-Chlorophenoxy)Phenyl)-2-Hydroxy-3,5-DIIodobenzamide 3-氯-4-(对氯苯氧基)-3,5-二碘水杨酰苯胺

CAS 22662-39-1 MFCD00682899

化学结构图

22662-39-1
SMILES: OC1C(=CC(I)=CC=1I)C(=O)NC1=CC(Cl)=C(C=C1)OC1C=CC(Cl)=CC=1

化学属性

Mol. FormulaC19H11Cl2I2NO3
Mol. Weight626
Melting Point173.0 to 177.0 deg-C

别名和识别编码

Chemical NameN-(3-Chloro-4-(4-Chlorophenoxy)Phenyl)-2-Hydroxy-3,5-DIIodobenzamide
CAS Number22662-39-1
Synonym Bovanide 3'-Chloro-4'-(p-chlorophenoxy)-3,5-diiodosalicylanilide Flukanide 雷复尼特 Benzamide, N-(3-chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodo- Rafoxanide ######## MK-990 Duofas Ranide 3'-Chloro-4'-(4-chlorophenoxy)-3,5-diiodosalicylanilide
MDL NumberMFCD00682899
PubChem Substance ID172089089
EC Number245-148-9
Chemical Name Translation3-氯-4-(对氯苯氧基)-3,5-二碘水杨酰苯胺
Wiswesser Line NotationQR BI DI FVMR CG DOR DG
Beilstein Registry Number2228187
Reaxys-RN2228187
Merck Number8097
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分类

  • Amines
  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, Environmental Standards, Insecticides, Others, Pesticides, Pesticides & Metabolites, R
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Environmental Standards, Insecticides, Others, Pesticides & Metabolites, Pesticides Standards, R

产品应用

  • Rafoxanide is a thyroid hormone receptor.

相关文献及参考

  • Bernal, J., et al.: Vitam. Horm., 71, 95 (2005),
  • Fujimoto, N., et al.: J. Endocrinol., 181, 77 (2005),
  • Hamers, T., et al.: Toxicol. Sci., 92, 157 (2006),

安全信息

RTECSVN7870000
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - cattle
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   REMVAY Revue d'Elevage et de Medicine Veterinaire des Pays Tropicaux.
   (Editions Vigot, 23 rue de l'Ecole-de-Medecine, F-75006 Paris, France) V.1- 
     1947-  Volume(issue)/page/year: 29,31,1976

系列性分类


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