Azelnidipine 阿折地平

CAS 123524-52-7 MFCD00865803

化学结构图

123524-52-7
SMILES: CC1NC(N)=C(C(C=1C(=O)OC(C)C)C1C=C(C=CC=1)[N+]([O-])=O)C(=O)OC1CN(C1)C(C1C=CC=CC=1)C1C=CC=CC=1

化学属性

Mol. FormulaC33H34N4O6
Mol. Weight583

别名和识别编码

Chemical NameAzelnidipine
CAS Number123524-52-7
Synonym CS 905 Azelnidipine ######## 2-Amino-1,4-dihydro-6-methyl-4-(3 nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) ester 2-Amino-1,4-dihydro-6-methyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(diphenylmethyl)-3-azetidinyl] 5-(1-methylethyl) ester CS-905 Calblock RS-9054
MDL NumberMFCD00865803
Chemical Name Translation阿折地平
Reaxys-RN7420123
Merck Number907
PubChem Substance ID253661997
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分类

  • Inhibitors
  • {SNA} AN-AZ, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Calcium Channel Modulators, Cell Biology, Cell Signaling and Neuroscience, Daiichi-Sankyo, Inhibitors and Activators, Ion Channels, Voltage-gated Ion Channels
  • {SNA} AN-AZ, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Calcium Channel Modulators, Daiichi-Sankyo, Inhibitors and Activators, Ion Channels, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Aromatics

产品应用

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相关文献及参考

  • Sugimoto, K. et al.: Int. J. Hypertens., No pp. (2010); Kain, V. et al.: Cardio. Diabetol., 9, 82 (2010); Kinouchi, K. et al.: Int. J. Hypertens., 284823, 11 (2011);

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312+P330
  • P305+P351+P338
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H318 Causes serious eye damage 严重伤害眼睛
RTECSUS7968332
Signal word Danger
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置；
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Approved Therapeutics/Drug Candidates - Cell Signaling and Neuroscience
  5. Daiichi-Sankyo - Approved Therapeutics/Drug Candidates

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