Pergolide 培高利特
CAS 66104-22-1 MFCD00867357
化学结构图
SMILES: CCCN1C[C@@H](C[C@H]2[C@H]1CC1=CNC3C=CC=C2C1=3)CSC
化学属性
| Mol. Formula | C19H26N2S |
|---|---|
| Mol. Weight | 314.49 |
| Appearance | XXXX solid powder |
| Solubility | Soluble in DMSO. |
别名和识别编码
| Chemical Name | Pergolide |
|---|---|
| MDL Number | MFCD00867357 |
| Reaxys-RN | 5091461 |
| Merck Number | 7162 |
| Chemical Name Translation | 培高利特 |
| PubChem Substance ID | 354333359 |
| Formula | C19H26N2S |
| Synonym | (8)8(methylthio)methyl6propylergoline |
| IUPAC Name | 9-((methylthio)methyl)-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline |
| InChIKey | YEHCICAEULNIGD-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H26N2S/c1-3-7-21-11-13(12-22-2)8-16-15-5-4-6-17-19(15)14(10-20-17)9-18(16)21/h4-6,10,13,16,18,20H,3,7-9,11-12H2,1-2H3 |
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产品应用
- Pergolide (Permax, Pergotoliderived) is an ergoline-based dopamine receptor agonist used in some countries for the treatment of Parkinson's disease. Parkinson's disease is associated with low levels of the neurotransmitter dopamine in the brain. Pergolide has some of the same effects as dopamine in the body. In 2007, pergolide was withdrawn from the U.S. market after several published studies revealed a link between the drug and increased rates of valvular dysfunction. (Source: http://en.wikipedia.org/wiki/Pergolide )
安全信息
- H300 Fatal if swallowed 吞食致命
GHS Symbol
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P201 Obtain special instructions before use. 使用前获取专门指示。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- P405 Store locked up. 上锁保管。
- P301+P310+P330
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
- P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P308+P313
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