芍药甙芍药苷 芍药苷
CAS 23180-57-6 MFCD00869331
化学结构图
SMILES: C[C@@]12C[C@@]3(O)O[C@@H](O1)[C@]1(COC(=O)C4C=CC=CC=4)[C@H]3C[C@@]12O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
化学属性
| Mol. Formula | C23H28O11 |
|---|---|
| Mol. Weight | 480.47 |
| Density | 1.63 |
别名和识别编码
| Chemical Name | 芍药甙芍药苷 |
|---|---|
| CAS Number | 23180-57-6 |
| EC Number | 245-476-2 |
| Synonym | Peoniflorin 芍药甙 5beta-[(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1alpha(2H)-yl-beta-D-glucopyranoside |
| MDL Number | MFCD00869331 |
| Beilstein Registry Number | 2384789 |
| Reaxys-RN | 6079909 |
| PubChem Substance ID | 125307355 |
| Chemical Name Translation | 芍药苷 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates P-Z, Cell Biology, Nutrition Research, Phytochemicals by Chemical Classification, Terpenes and Terpenoids (Isoprenoids)
- {SNA} Carbohydrates A to Z, Carbohydrates P-Z, Phytochemicals by Chemical Classification, Terpenes and Terpenoids (Isoprenoids), 生化试剂, 碳水化合物, 细胞生物学, 营养研究
- {SNA} Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates P-Z, Nutrition Research, Phytochemicals by Chemical Classification, Terpenes and Terpenoids (Isoprenoids)
产品应用
- 中药成分来自芍药的根。中药上其解痉止痛的属性。抗心肌缺血、具抗凝抑制血小板聚集作用；解痉作用；镇痛、镇静作用；抗炎、抗溃疡作用；保肝作用；调节免疫力作用和抗高血糖作用；耐缺氧作用等。
- 临床应用：用于冠心病的治疗；用于老年性疾病，增强体质与免疫功能、抗炎止咳、祛痰平喘等方面，尤其是老年慢性呼吸道疾病的治疗中可作辅助药物。
相关文献及参考
- [2]. Cao BY, et al. Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway. J Ethnopharmacol. 2010;131(1):122-129.
- [3]. Yan D, et al. Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress Chaperones. 2004;9(4):378-389.
- [1]. Xiang Y, et al. Paeoniflorin: a monoterpene glycoside from plants of Paeoniaceae family with diverse anticancer activities. J Pharm Pharmacol. 2020;72(4):483-495.
- [1]. Xiang Y, et al. Paeoniflorin: a monoterpene glycoside from plants of Paeoniaceae family with diverse anticancer activities. J Pharm Pharmacol. 2020;72(4):483-495.
- [2]. Cao BY, et al. Paeoniflorin, a potent natural compound, protects PC12 cells from MPP+ and acidic damage via autophagic pathway. J Ethnopharmacol. 2010;131(1):122-129.
- [3]. Yan D, et al. Paeoniflorin, a novel heat shock protein-inducing compound. Cell Stress Chaperones. 2004;9(4):378-389.
安全信息
GHS Symbol
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3530 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 89,899,1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 9530 mg/kg TOXIC EFFECTS : Behavioral - sleep Behavioral - somnolence (general depressed activity) REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 89,899,1969
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