Ercalcitriol 骨钙三醇

CAS 60133-18-8 MFCD00869499

化学结构图

60133-18-8
SMILES: CC(C)(O)[C@@H](C)/C=C/[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@@H](O)C[C@H](O)C/1=C

化学属性

Mol. FormulaC28H44O3
Mol. Weight428.65

别名和识别编码

Chemical NameErcalcitriol
CAS Number60133-18-8
Synonym ######## 1α,25-Dihydroxycalciferol 1α,25-Dihydroxycalciferol 1α,25-Dihydroxycalciferol solution 1α,25-Dihydroxyvitamin D2
MDL NumberMFCD00869499
PubChem Substance ID57647692
Beilstein Registry Number5635017
Chemical Name Translation骨钙三醇
EC Number200-578-6
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分类

  • {SNA} Vitamin D, Vitamin D2, Vitamins, 代谢组学,
  • Metabolic Pathways, Metabolomics, Nutrition Research, Steroid Metabolism, Vitamin D, Vitamin D2,
  • {SNA} Alphabetical Listings, D, Stable Isotopes, Vitamins
  • {SNA} Vitamin D, Vitamins,

产品应用

  • The active metabolite of Vitamin D2 (V676040).

相关文献及参考

  • [2]. Rambeck et al (1984) Biological activity of 1 alpha,25-dihydroxyergocalciferol in rachitic chicks and in rats. Int.J.Vitamin.Nutr.Res. 54 135.
  • [3]. Shamik J. Parikh, Marni Edelman, Gabriel I. Uwaifo et al. The Relationship between Obesity and Serum 1,25-Dihydroxy Vitamin D Concentrations in Healthy Adults. The Journal of Clinical Endocrinology & Metabolism March 1, 2004 vol. 89 no. 3 1196-1199
  • [4]. Daniel W. Coyne, Marvin Grieff, Shubhada N. Ahya et al. Differential effects of acute administration of 19-Nor-1,25-dihydroxy-vitamin D2 and 1,25-dihydroxy-vitamin D3 on serum calcium and phosphorus in hemodialysis patients. American Journal of Kidney Diseases. December 2002,Volume 40, Issue 6 , Pages 1283-1288
  • Armas LA, Heaney RP., Vitamin D: the iceberg nutrient. J. Ren. Nutr. 21 , 134-139, (2011) 摘要
  • Bartley J., Vitamin D: emerging roles in infection and immunity. Expert Rev. Anti. Infect. Ther. 8 , 1359-1369, (2010) 摘要
  • Cuppari L,

安全信息

WGK Germany1
GHS Symbol
Precautionary statements
  • P301+P310
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P311 Call a POISON CENTER or doctor/physician. 呼叫解毒中心或医生/医师。
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P337+P313
  • P403+P235
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P284 Wear respiratory protection.? 佩戴呼吸保护装置。
  • P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
Hazard statements
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H301+H311
  • H330 Fatal if inhaled 吸入致命
  • H372 Causes damage to organs through prolonged or repeated exposure 长期或频繁接触会损伤器官
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
  • H331 Toxic if inhaled 吸入中毒
  • H311 Toxic in contact with skin 皮肤接触中毒
  • H301 Toxic if swallowed 吞食有毒
Hazard Codes T T+ F
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Signal word Danger
Safety Statements
  • S7 Keep container tightly closed 保存在严格密闭容器中;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
Risk Statements
  • R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
  • R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
  • R48/25
  • R26 Very toxic by inhalation 吸入极毒
  • R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
  • R11 Highly flammable 非常易燃

系列性分类


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