(S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate sulfate (S)-(+)-(2-氯苯基)(6,7-二氢-4H-噻吩[3,2-C]吡啶-5-基)乙酸甲酯硫酸盐

CAS 120202-66-6 MFCD00876395

化学结构图

120202-66-6
SMILES: COC(=O)[C@H](C1C=CC=CC=1Cl)N1CC2C=CSC=2CC1.OS(O)(=O)=O

化学属性

Mol. FormulaC16H16ClNO2S.H2SO4
Mol. Weight420

别名和识别编码

Chemical Name(S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate sulfate
CAS Number120202-66-6
Alfabeta NameCLOPIDOGRELBISULFATE
MDL NumberMFCD00876395
Synonym (S)-(+)-Methyl 2-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate hydrogensulfate Methyl (S)-(+)-2-(2-Chlorophenyl)-2-[6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl]acetate Sulfate
Reaxys-RN9967887
PubChem Substance ID125308051
Chemical Name Translation(S)-(+)-(2-氯苯基)(6,7-二氢-4H-噻吩[3,2-C]吡啶-5-基)乙酸甲酯硫酸盐
Beilstein Registry Number9967887
LabNetwork Molecule IDLN00149725
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分类

  • {SNA} Adenosines/P2 Nucleotide Receptor - Antagonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Antagonists, Anticoagulants, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Blood, Bristol-Myers Squibb, CI-CZ, Diversification Ready Pharma-Developed Compounds, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Immune Cell Signaling and Blood, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, Sanofi Aventis, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • {SNA} Analytical Standards,
  • Adenosines/P2 Nucleotide Receptor - Antagonists,

相关文献及参考

  • [2]. Roald, H.E., et al., Clopidogrel--a platelet inhibitor which inhibits thrombogenesis in non-anticoagulated human blood independently of the blood flow conditions. Thromb Haemost, 1994. 71(5): p. 655-62.
  • [3]. Ramadan, R., et al., Effects of Clopidogrel Therapy on Oxidative Stress, Inflammation, Vascular Function and Progenitor Cells in Stable Coronary Artery Disease. J Cardiovasc Pharmacol, 2013.
  • Bhatt, D. L., et al., Clopidogrel with or without omeprazole in coronary artery disease. New Engl. J. Med. 363 , 1909-1917, (2010)
  • Cornelissen, I., et al., Roles and interactions among protease-activated receptors and P2ry12 in hemostasis and thrombosis. Proc. Natl. Acad. Sci. U. S. A. 107 , 18605-18610, (2010) 摘要
  • [1]. Geiger, J., et al., Speci
  • [1]. Geiger, J., et al., Specific impairment of human platelet P2Y(AC) ADP receptor-mediated signaling by the antiplatelet drug clopidogrel. Arterioscler Thromb Vasc Biol, 1999. 19(8): p. 2007-11.

安全信息

Warnings IRRITANT
WGK Germany3
Storage condition 0-10 0-10°C
Signal word
Hazard statements
  • H303 May be harmfully swallowed 吞食可能有害
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。
Packing GroupII
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;

系列性分类


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