1-(5-Ethyl-2-Hydroxy-4-((6-Methyl-6-(2H-Tetrazol-5-Yl)Heptyl)Oxy)Phenyl)Ethan-1-One 1-(5-乙基-2-羟基-4-((6-甲基-6-(2H-四唑-5-基)庚基)氧基)苯基)乙-1-酮
CAS 117690-79-6 MFCD00876422
化学结构图
SMILES: CC(=O)C1=CC(CC)=C(C=C1O)OCCCCCC(C)(C)C1NN=NN=1
化学属性
| Mol. Formula | C19H28N4O3 |
|---|---|
| Mol. Weight | 360.45 |
别名和识别编码
| Chemical Name | 1-(5-Ethyl-2-Hydroxy-4-((6-Methyl-6-(2H-Tetrazol-5-Yl)Heptyl)Oxy)Phenyl)Ethan-1-One |
|---|---|
| Synonym | 1-(5-Ethyl-2-hydroxy-4-(6-methyl-6-(1H-tetrazol-5-yl)heptyloxy)phenyl)ethanone LY255283 |
| MDL Number | MFCD00876422 |
| CAS Number | 117690-79-6 |
| PubChem Substance ID | 329817396 |
| Chemical Name Translation | 1-(5-乙基-2-羟基-4-((6-甲基-6-(2H-四唑-5-基)庚基)氧基)苯基)乙-1-酮 |
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分类
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Eli Lilly, Enzyme Inhibitors, L, Lipids in Cell Signaling, Lipoxygenase, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Cell Biology, Cell Signaling and Neuroscience, Eli Lilly, Enzyme Inhibitors, Lipids in Cell Signaling, Lipoxygenase
相关文献及参考
- [2]. S A Silbaugh, et al. Pulmonary actions of LY255283, a leukotriene B4 receptor antagonist. Eur J Pharmacol. 1992 Nov 13;223(1):57-64.
- [3]. P S Wollert, et al. LY255283, a novel leukotriene B4 receptor antagonist, limits activation of neutrophils and prevents acute lung injury induced by endotoxin in pigs. Surgery. 1993 Aug;114(2):191-8.
- [4]. Eun-Young Kim, et al. BLT2 promotes the invasion and metastasis of aggressive bladder cancer cells through a reactive oxygen species-linked pathway. Free Radic Biol Med. 2010 Sep 15;49(6):1072-81.
- [1]. R M Schultz, et al. Effects of two leukotriene B4 (LTB4) receptor antagonists (LY255283 and SC-41930) on LTB4-induced human neutrophil adhesion and superoxide produc
- [1]. R M Schultz, et al. Effects of two leukotriene B4 (LTB4) receptor antagonists (LY255283 and SC-41930) on LTB4-induced human neutrophil adhesion and superoxide production. Prostaglandins Leukot Essent Fatty Acids. 1991 Aug;43(4):267-71.
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