4-(2-((7-Amino-2-(Furan-2-Yl)-[1,2,4]Triazolo[1,5-A][1,3,5]Triazin-5-Yl)Amino)Ethyl)Phenol 4-(2-((7-氨基-2-(呋喃-2-基)-[1,2,4]三唑并[1,5-a][1,3,5]t三嗪-5-基)氨基)乙基)苯酚

CAS 139180-30-6 MFCD00908394

化学结构图

139180-30-6
SMILES: NC1=NC(NCCC2C=CC(O)=CC=2)=NC2=NC(=NN21)C1=CC=CO1

化学属性

Mol. FormulaC16H15N7O2
Mol. Weight337.34

别名和识别编码

Chemical Name4-(2-((7-Amino-2-(Furan-2-Yl)-[1,2,4]Triazolo[1,5-A][1,3,5]Triazin-5-Yl)Amino)Ethyl)Phenol
Synonym 4-(-2-[7-amino-2-{2-furyl}{1,2,4}triazolo{2,3-a} {1,3,5}triazin-5-yl-amino]ethyl)phenol ZM 241385
MDL NumberMFCD00908394
PubChem Substance ID329831597
CAS Number139180-30-6
Chemical Name Translation4-(2-((7-氨基-2-(呋喃-2-基)-[1,2,4]三唑并[1,5-a][1,3,5]t三嗪-5-基)氨基)乙基)苯酚
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信息真实价格透明    资金保障    专业采购外包团队在线服务   
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分类

  • {SNA} Adenosines/P2 Nucleotide Receptor - Antagonists, Adenosines/P2 Nucleotide Receptors (Purinergics), Antagonists, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitter
  • {SNA} Adenosines/P2 Nucleotide Receptor - Antagonists, Ad

相关文献及参考

  • [2]. Linden J, et al. Characterization of human A(2B) adenosine receptors: radioligandbinding, western blotting, and coupling to G(q) in human embryonickidney 293 cells and HMC-1 mast cells. Mol Pharmacol. 1999 Oct;56(4):705-13.
  • [3]. Poucher SM, et al. The in vitro pharmacology of ZM 241385, a potent, non-xanthine A2a selective adenosinereceptor antagonist. Br J Pharmacol. 1995 Jul;115(6):1096-102.
  • [4]. Ludwig S, et al. Impact of combination immunochemotherapies on progression of 4NQO-induced murine oral squamous cell carcinoma. Cancer Immunol Immunother. 2019 Jul;68(7):1133-1141.
  • [1]. Wang Z, et al. Static magnetic field exposure reproduces cellular effects of the Parkinson's disease drugcandidate ZM241385. PLoS One. 2010 Nov 8;5(11):e13883. doi
  • [1]. Wang Z, et al. Static magnetic field exposure reproduces cellular effects of the Parkinson's disease drugcandidate ZM241385. PLoS One. 2010 Nov 8;5(11):e13883. doi: 10.1371/journal.pone.0013883.

安全信息

Safety Statements
  • S46 If swallowed, seek medical advice immediately and show this container or label 食入时，立即求医并出示容器/标签；
GHS Symbol
Precautionary statements
  • P301+P310
Hazard statements
  • H301 Toxic if swallowed 吞食有毒
WGK Germany3
Signal word Danger
Hazard Codes T
Risk Statements
  • R25 Toxic if swallowed 吞咽有毒

系列性分类

  1. Life Science 生命科学
  2. Biochemicals and Reagents 生化试剂
  3. Proteins and Derivatives - Biochemicals and Reagents
  4. Membrane Protein Biology Tools - Proteins and Derivatives
  5. GPCR Proteins, Modulators and Antibodies - Membrane Protein Biology Tools
  6. GPCR Modulators - GPCR Proteins, Modulators and Antibodies
  7. Adenosines/P2 Nucleotide Receptor - Antagonists - GPCR Modulators
  1. Medical Research Areas
  2. GPCR & G Protein
  3. Adenosine Receptor  (腺苷受体)

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