2-(Phosphonomethyl)Pentanedioic Acid 2-(膦酰基甲基)戊二酸
CAS 173039-10-6 MFCD00940167
化学结构图
SMILES: O=C(O)CCC(CP(=O)(O)O)C(=O)O
化学属性
| Mol. Formula | C6H11O7P |
|---|---|
| Mol. Weight | 226.12 |
别名和识别编码
| Chemical Name | 2-(Phosphonomethyl)Pentanedioic Acid |
|---|---|
| Chemical Name Translation | 2-(膦酰基甲基)戊二酸 |
| PubChem Substance ID | 10130754 |
| InChI | InChI=1S/C6H11O7P/c7-5(8)2-1-4(6(9)10)3-14(11,12)13/h4H,1-3H2,(H,7,8)(H,9,10)(H2,11,12,13) |
| Synonym | 2-(phosphonomethyl)pentanedioic acid 2-PMPA cpd |
| LabNetwork Molecule ID | LN00193368 |
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相关文献及参考
- [2]. Zuo D, et al. Existence of glia mitigated ketamine-induced neurotoxicity in neuron-glia mixed cultures of neonatal rat cortex and the glia-mediated protective effect of 2-PMPA. Neurotoxicology. 2014 Sep;44:218-30.
- [3]. Baslow MH, et al. 2-PMPA, a NAAG peptidase inhibitor, attenuates magnetic resonance BOLD signals in brain of anesthetized mice: evidence of a link between neuron NAAG release and hyperemia. J Mol Neurosci. 2005;26(1):1-15.
- [4]. Nagel J, et al. Effects of NAAG peptidase inhibitor 2-PMPA in model chronic pain-relation to brain concentration. Neuropharmacology. 2006 Dec;51(7-8):1163-71.
- [1]. Rais R, et al. Bioanalytical method for evaluating the pharmacokinetics of the GCP-II inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA). J Pharm Bio
- [1]. Rais R, et al. Bioanalytical method for evaluating the pharmacokinetics of the GCP-II inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA). J Pharm Biomed Anal. 2014 Jan;88:162-9.
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