IRL-2500 (S)-2-((R)-3-([1,1'-联苯]-4-基)-2-(N,3,5-三甲基苯甲酰胺基)丙酰胺基)-3-(1H-吲哚-3-基)丙酸

CAS 169545-27-1 MFCD00948945

化学结构图

169545-27-1
SMILES: CC1=CC(=CC(C)=C1)C(=O)N(C)[C@H](CC1C=CC(=CC=1)C1C=CC=CC=1)C(=O)N[C@@H](CC1=CNC2C=CC=CC1=2)C(O)=O

化学属性

Mol. FormulaC36H35N3O4
Mol. Weight573.69

别名和识别编码

Chemical NameIRL-2500
Chemical Name Translation(S)-2-((R)-3-([1,1'-联苯]-4-基)-2-(N,3,5-三甲基苯甲酰胺基)丙酰胺基)-3-(1H-吲哚-3-基)丙酸
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相关文献及参考

  • [2]. Webb RL, et al. Effects of the ETB-selective antagonist IRL 2500 in conscious spontaneously hypertensive and Wistar-Kyoto rats.J Cardiovasc Pharmacol. 1995;26 Suppl 3:S389-92.
  • [1]. Balwierczak JL, et al. Characterization of a potent and selective endothelin-B receptor antagonist, IRL 2500.J Cardiovasc Pharmacol. 1995;26 Suppl 3:S393-6.
  • [1]. Balwierczak JL, et al. Characterization of a potent and selective endothelin-B receptor antagonist, IRL 2500.J Cardiovasc Pharmacol. 1995;26 Suppl 3:S393-6.
  • [2]. Webb RL, et al. Effects of the ETB-selective antagonist IRL 2500 in conscious spontaneously hypertensive and Wistar-Kyoto rats.J Cardiovasc Pharmacol. 1995;26 Suppl 3:S389-92.

系列性分类

  1. Medical Research Areas
  2. GPCR & G Protein
  3. Endothelin Receptor  (内皮素受体)

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