• S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；

• R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

• P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1000 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Endocrine - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(i

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Endocrine - tumors
   Reproductive - Tumorigenic effects - ovarian tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2500 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 750 mg/kg/I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Liver - tumors
   Reproductive - Tumorigenic effects - uterine tumors
REFERENCE :
   AMPLAO AMA Archives of Pathology.  (Chicago, IL)  V.50(4)-69, 1950-60.  For
   publisher information, see APLMAS.  Volume(issue)/page/year: 67,589,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 gm/kg
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 53A,486,1974

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3 gm/kg

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KHFZAN Khimiko-Farmatsevticheskii Zhurnal.  Chemical Pharmaceutical Journal.
    For English translation, see PCJOAU.  (V/O Mezhdunarodnaya Kniga, 113095
   Moscow, USSR)  V.1-    1967-  Volume(issue)/page/year: 19,212,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >40 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAONAU FAO Nutrition Meetings Report Series.  (Rome, Italy)  No.?-57,
   1948-77.  Discontinued.  Volume(issue)/page/year: 40,164,1967

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BMDOAI Biomaterials, Medical Devices, and Artificial Organs.  (New York)
   V.1-14, 1973-86.  For publisher information, see BACOEZ.
   Volume(issue)/page/year: 12,1,1984