PHE-PSI(CH2-NH)-GLY-GLY-PHE-THR-GLY-ALA-ARG-LYS-SER-ALA-ARG-LYS-NH2

CAS N/A MFCD01631267

化学结构图

N/A
SMILES: C[C@@H](O)[C@H](NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)CNC(=O)CNC[C@@H](N)CC1C=CC=CC=1)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(N)=O

化学属性

Mol. FormulaC61H101N22O14
Mol. Weight1366.59

别名和识别编码

Chemical Name[Phe1-ψ(CH2-NH)-Gly2]-Nociceptin Fragment 1-13 amide
MDL NumberMFCD01631267
Synonym
PubChem Substance ID329818698
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分类

  • {SNA} Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Opioid Peptides, Other Opioid Peptides, Peptides and Proteins, Peptides for Cell Biology
  • {SNA} Bioactive Small Molecule Alphabetical Index, N, Neuropeptides, Opioid Peptides, Other Opioid Peptides,

相关文献及参考

  • Grisel, J.E., et al., Phe 1 -ψ(CH 2 -NH)-Gly 2 ]nociceptin (1-13)-NH 2 acts as an agonist of the orphanin FQ/nociceptin receptor in vivo . Eur. J. Pharmacol. 357 , R1-3, (1998) 摘要
  • Guerrini, R., et al., A new selective antagonist of the nociceptin receptor. Br. J. Pharmacol. 123 , 163, (1998) 摘要
  • Lin, B., Nociceptin receptor activation produces nitric oxide-mediated systemic hypotension. Life Sci. 66 , PL99-PL104, (2000) 摘要
  • Okawa, H., Comparison of the effects of [Phe 1 -ψ(CH 2 -NH)-Gly 2 ]nociceptin (1-13)-NH 2 in rat brain rat vas deferens and CHO cells expressing recombinant human nociceptin receptors. Br. J. Pharmacol. 127 , 123-130, (1999) 摘要
  • Salvadori, S., et al., Structure-activity studies on nociceptin/orphanin FQ: from full agonist, to partial agonist, to pure antagonist. Farmaco 54 , 810-825, (1999) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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