2,6-Piperazinedione, 4,4'-(1,2-dimethylethylene)di-,meso- ICRF-193

CAS 21416-88-6 MFCD01702964

化学结构图

21416-88-6
SMILES: C[C@@H]([C@@H](C)N1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1 |&1:1,2|

化学属性

Mol. FormulaC12H18N4O4
Mol. Weight282.30

别名和识别编码

Chemical NameICRF-193 apoptosis inducer, arabinosidase substrate
Synonym 2,6-Piperazinedione, 4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-, (R*,S*)- ICRF 193 ICRF-193 meso-4,4'-(3,2-butanediyl)-bis(2,6-piperazinedione)
MDL NumberMFCD01702964
PubChem Substance ID24896062
CAS Number21416-88-6
Beilstein Registry Number3981691
Chemical Name TranslationICRF-193
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分类

  • {SNA} Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Gene Regulation and Expression, R to Z, RNA-Protein Translation Inhibitors, Topoisomerase II, Topoisomerase II-B, 生化试剂, 细胞信号转导和神经科学, 细胞生物学, 酶、抑制剂和底物
  • {SNA} Gene Regulation and Expression, RNA-Pr

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P301+P310
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
Hazard statements
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
  • H301 Toxic if swallowed 吞食有毒
RTECSTL6380200
Signal word Danger
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Safety Statements
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Hazard Codes Xn
Risk Statements
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 500 ug/L
REFERENCE :
   IJCNAW International Journal of Cancer.  (International Union Against
   Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland)  V.1-    1966-
   Volume(issue)/page/year: 5,47,1970

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Gene Regulation and Expression - Cell Signaling and Neuroscience
  5. RNA-Protein Translation Inhibitors - Gene Regulation and Expression

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