L-Pinaverium Bromide 匹维溴铵

CAS 53251-94-8 MFCD53251948

化学结构图

53251-94-8
SMILES: [Br-].COC1=CC(Br)=C(C[N+]2(CCOCCC3CCC4CC3C4(C)C)CCOCC2)C=C1OC

化学属性

Mol. Weight591.50
Mol. FormulaC26H41BrNO4.Br

别名和识别编码

CAS Number53251-94-8
Chemical NameL-Pinaverium Bromide
Synonym LAT-1717 4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]-hept-2-yl)ethoxy]ethyl]morpholinium Bromide Dicetel Pinaverium bromide LAT 1717
Wiswesser Line NotationL46 ATJ A1 A1 E2O2- AT6K DOTJ A1R BE DO1 EO1 &E&24/47
Chemical Name Translation匹维溴铵
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals,

产品应用

  • Spasmolytic agent with low incidence of anticholinergic effects. Antispasmodic.

相关文献及参考

  • Jacquot, C., et al.: Eur. J. Med. Chem., 13, 61 (1978),
  • Bretaudeau, J., et al.: J. Pharmacol., 11, 233 (1980),
  • Bertrand, J., et al.: Therapie, 36, 555 (1981),

安全信息

RTECSQF2810000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 504 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 40,133,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 37 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 9,182,1974

系列性分类


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