Dl-Lysine Acetylsalicylate 赖氨匹林

CAS 62952-06-1 MFCD62952061

化学结构图

62952-06-1
SMILES: CC(=O)OC1C=CC=CC=1C(O)=O.NCCCC[C@H](N)C(O)=O

化学属性

Mol. Weight326.39
Mol. FormulaC9H8O4.C6H14N2O2

别名和识别编码

CAS Number62952-06-1
Chemical NameDl-Lysine Acetylsalicylate
Synonym Venopirin Aspisol Aspirin DL-lysine DL-Lysine acetylsalicylic acid salt DL-Lysine acetylsalicylate 2-(Acetyloxy)benzoate DL-Lysine, mono(2-(acetyloxy)benzoate)
Chemical Name Translation赖氨匹林
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分类

  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Non-steroidal anti-inflammatory drugs (NSAIDs) may inhibit cancer growth.

相关文献及参考

  • Korttila, K., et al.: Br. J. Anaesth, 52, 613 (1980),
  • Diaz, C., et al.: Clin. Ther., 4, 121 (1981),
  • Wolff, F., et al.: Arch. Gynecol., 233, 15 (1982),

安全信息

RTECSOL5675000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 950 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 6,1275,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 21,341,1987

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3270 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan)  V.1-    1972-
   Volume(issue)/page/year: 6,1275,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4350 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   YACHDS Yakuri to Chiryo.  Pharmacology and Therapeutics.  (Raifu Saiensu
   Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo

TYPE O

系列性分类

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