Febantel 非班太尔

CAS 58306-30-2 MFCD01738527

化学结构图

58306-30-2
SMILES: COC(=O)/N=C(/NC(=O)OC)\NC1C=CC(=CC=1NC(=O)COC)SC1C=CC=CC=1

化学属性

Mol. FormulaC20H22N4O6S
Mol. Weight446.48
Melting Point125.0 to 129.0 deg-C

别名和识别编码

Chemical NameFebantel
CAS Number58306-30-2
Synonym N-{2-[2,3-双-(甲氧羰基)-胍基]-5-(苯硫基)-苯基}-2-甲氧基乙酰胺 苯硫胍 Bay Vh 5757 Febantel Rintal BAY Vh5757 [[2-[(Methoxyacetyl)amino]-4-(phenylthio)phenyl]carbonimidoyl]bis-carbamic Acid Dimethyl Ester N-(2-(2,3-Bis-(methoxycarbonyl)-guanidino)-5-(phenylthio)-phenyl)-2-methoxyacetamide
MDL NumberMFCD01738527
PubChem Substance ID253661507
EC Number261-205-0
Chemical Name Translation非班太尔
Wiswesser Line Notation1OVNUYMVO1&MR DSR& BMV1O1
Beilstein Registry Number2195764
Reaxys-RN13258677
Merck Number3944
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分类

  • Pharmaceuticals
  • {SNA} Analytical Standards, Antibiotics Standards, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, F, FA - FL
  • Intermediates & Fine Chemicals,

产品应用

  • Used as an anthelmintic.

相关文献及参考

  • Thomas, H.: Res. Vet. Sci., 25, 290 (1978),

安全信息

RTECSFB3955000
GHS Symbol
Hazard statements
  • H302 Harmful if swallowed 吞食有害
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes Xn
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : >200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneo

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 28

系列性分类


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