N,N,N,N-Tetramethyl-O-(N-Succinimidyl)Uronium Hexafluorophosphate N,N,N-四甲基脲-O-(N-琥珀酸亚胺基)六氟磷酸盐(HSTU)

CAS 265651-18-1 MFCD01863753

化学结构图

265651-18-1
SMILES: CN(C)C(ON1C(=O)CCC1=O)=[N+](C)C.F[P-](F)(F)(F)(F)F

化学属性

Mol. FormulaC9H16F6N3O3P
Mol. Weight359.21
Melting Point218-221
TSCANo

别名和识别编码

Chemical NameN,N,N,N-Tetramethyl-O-(N-Succinimidyl)Uronium Hexafluorophosphate
Synonym N,N,N',N'-四甲基-O-(N-琥珀酸亚胺基)脲六氟磷酸盐 N,N,N′,N′-四甲基脲-O-(N-琥珀酸亚胺基)六氟磷酸盐 O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium Hexafluorophosphate
MDL NumberMFCD01863753
PubChem Substance ID172088955
CAS Number265651-18-1
Chemical Name TranslationN,N,N-四甲基脲-O-(N-琥珀酸亚胺基)六氟磷酸盐(HSTU)
Reaxys-RN15594359
Beilstein Registry Number15594359
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分类

  • {SNA} Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry, Peptide Coupling, Phosphonium/Uronium/Formamidinium, Synthetic Reagents

产品应用

  • 多肽合成偶联试剂

相关文献及参考

  • 1. Sjoerd Hak, et al Eur. J. Pharm. Biopharm. 72 , 397-404, (2009)
  • 2. Herman J. Gruber, et al Bioconjug. Chem. 11 , 161-166, (2000)
  • 3. G. Tang, et al J. Labelled Comp. Radiopharm. 51 , 68-71, (2008)
  • 4. R. Knorr et al. Tetrahedron Lett. 30 , 1927, (1989)
  • 5. W. Bannwarth, R. Knorr Tetrahedron Lett. 32 , 1157, (1991)

安全信息

Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352+P332+P313+P362+P364
  • P304+P340+P312
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用
Signal word Warning
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
WGK Germany3
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Storage condition Moisture Sensitive <0°C 储存温度 -20°C

系列性分类


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