H-SER-ARG-THR-HIS-ARG-HIS-SER-MET-GLU-ILE-ARG-THR-PRO-ASP-ILE-ASN-PRO-ALA-TRP-TYR-ALA-SER-ARG-GLY-ILE-ARG-PRO-VAL-GLY-ARG-PHE-NH2

CAS 235433-36-0 MFCD02094631

化学结构图

235433-36-0
SMILES: CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CC1=CNC2C=CC=CC1=2)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=CC=C1)C(N)=O

化学属性

Mol. FormulaC160H252N56O42S
Mol. Weight3664.13

别名和识别编码

Chemical NameProlactin-releasing Peptide human
Synonym PrRP20 PrRP31
MDL NumberMFCD02094631
LabNetwork Molecule IDLN02126440
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分类

  • Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology, PrRP, Prolactin-releasing Peptide, Releasing Factors
  • {SNA} Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology,

相关文献及参考

  • Hinuma, S., et al., The quest for novel bioactive peptides utilizing orphan seven-transmembrane-domain receptors. J. Mol. Med. 77 , 495-504, (1999) 摘要
  • Hizume, T., et al., Involvement of prolactin-releasing peptide in the preovulatory luteinizing hormone and prolactin surges in the rat. Biochem. Biophys. Res. Commun. 279 , 35-39, (2000) 摘要
  • Kimura, A., et al., Prolactin-releasing peptide activation of the prolactin promoter is differentially mediated by extracellular signal-regulated protein kinase and c-Jun N-terminal protein kinase. J. Biol. Chem. 275 , 3667-3674, (2000) 摘要
  • Matsumoto, H., et al., Stimulation of corticotropin-releasing hormone-mediated adrenocorticotropin secretion by central administration of prolactin-releasing peptide in rats. Neurosci. Lett. 285 , 234-238, (2000) 摘要
  • Morales, T., et al., Prolactin-releasing peptide is expressed in afferents to the endocrine hypothalamus, but not in neurosecretory neurones. J. Neuroendocrinol. 12 , 131-140, (2000) 摘要
  • Seal, L.J., et al., Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. Endocrinology 141 , 1909-1912, (2000) 摘要

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

  1. Neuropeptides - Peptides for Cell Biology
  2. Releasing Factors - Neuropeptides
  3. PrRP - Releasing Factors
  4. Prolactin-releasing Peptide - PrRP
  1. Neuropeptides - Peptides for Cell Biology
  2. Releasing Factors - Neuropeptides
  3. PrRP - Releasing Factors
  4. Prolactin-releasing Peptide Fragment - PrRP
  1. Releasing Factors - Peptides for Cell Biology
  2. PrRP - Releasing Factors

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