2-Fluoro-6-methoxyphenylboronic acid 2-氟-6-甲氧基苯硼酸

CAS 78495-63-3 MFCD02179483

化学结构图

78495-63-3
SMILES: COC1C=CC=C(F)C=1B(O)O

化学属性

Mol. FormulaC7
Mol. Weight170
Melting Point120-125 °C (lit.)
TSCANo

别名和识别编码

Chemical Name2-Fluoro-6-methoxyphenylboronic acid
CAS Number78495-63-3
Alfabeta NameFLUOROMETHOXYPHENYLBORONICACID 26---
MDL NumberMFCD02179483
Synonym 2-Fluoro-6-methyloxyphenylboronic acid 6-Fluoro-2-methoxyphenylboronic acid 2-Fluoro-6-methyloxyphenylboronic acid 2-氟-6-甲氧基苯硼酸 6-Fluoro-2-methoxyphenylboronic acid 2-Fluoro-6-methoxyphenylboronic acid
PubChem Substance ID253659960
Chemical Name Translation2-氟-6-甲氧基苯硼酸
Reaxys-RN9192698
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分类

  • Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents
  • {SA} Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organometallic Reagents

相关文献及参考

  • 1. Alhambra, C.; et al., Development and SAR of functionally selective allosteric modulators of GABAA receptors Bioorg. Med. Chem. 19 , 2927-2938, (2011)
  • 2. Dubost, E.; et al., General method for the synthesis of substituted phenanthridin-6(5H)-ones using a KOH-mediated anionic ring closure as the key step Tetrahedron 66 , 5008-5016, (2010)
  • 3. Palmer, B. D.; et al., Synthesis and structure-activity studies of biphenyl analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824) J. Med. Chem. 53 , 282-294, (2010)
  • 4. Palmer, B. D.; et al., 4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione Inhibitors of the Checkpoint Kinase Wee1. Structure-Activity Relationships for Chromophore Modification and Phenyl Ring Substitution J. Med. Chem. 49 , 4896-4911, (2006)

安全信息

Warnings IRRITANT
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Signal word
GHS Symbol
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P302+P350
  • P302+P352+P332+P313+P362+P364
  • P305+P351+P338
  • P305+P351+P338+P337+P313
  • P332+P313
  • P337+P313
  • P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服,清洗后方可重新使用

系列性分类


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