5-Fluoro-2-Oxindole 5-氟吲哚-2-酮

CAS 56341-41-4 MFCD02179598

化学结构图

56341-41-4
SMILES: O=C1CC2C=C(F)C=CC=2N1

化学属性

Mol. FormulaC8
Mol. Weight151
Melting Point143.0 to 147.0 deg-C
Density1.311
TSCANo

别名和识别编码

Chemical Name5-Fluoro-2-Oxindole
CAS Number56341-41-4
Alfabeta NameFLUOROOXINDOLE 5-
MDL NumberMFCD02179598
Synonym 5-Fluoro-1,3-dihydro-indol-2-one 5-氟吲哚-2-酮 5-Fluoro-1,3-dihydroindol-2-one 5-氟吲哚酮,5-氟吲哚-2-酮, 5-氟-1,3-二氢吲哚-2-酮, 5-氟氧化吲哚 5-Fluoro-2,3-dihydro-2-oxoindole 5-Fluoro-1,3-dihydroindol-2-one 5-Fluoro-2,3-dihydro-2-oxoindole
PubChem Substance ID87560880
EC Number250-023-7
Beilstein Registry Number21(5)8,13
Chemical Name Translation5-氟吲哚-2-酮
Reaxys-RN1526789
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分类

  • {SNA} Building Blocks, C7 to C9, Chemical Synthesis, Fluorinated Building Blocks, Heterocyclic Building Blocks, Heterocyclic Fluorinated Building Blocks, Indoles, Other Fluorinated Heterocycles
  • Building Blocks, C7 to C9, Chemical Synthesis, Fluorinated Building Blocks, Heterocyclic Building Blocks,

相关文献及参考

  • 10. Zhang, W.; Go, M.-L., Functionalized 3-benzylidene-indolin-2-ones: Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1) with antiproliferative activity Bioorg. Med. Chem. 17
  • 6. Chiang, C.-C.; et al., Discovery of Pyrrole-Indolin-2-ones as Aurora Kinase Inhibitors with a Different Inhibition Profile J. Med. Chem. 53 , 5929, (2010) 摘要
  • 7. Wang, Z.-H.; et al., Synthesis and Biological Evaluation of 7-Azaisoindigo Derivatives Arch. Pharm. (Weinheim) 343 , 160, (2010)
  • Beilstein:21(5)8,13

安全信息

Warnings IRRITANT, KEEP COLD
WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Signal word Warning
GHS Symbol
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338

系列性分类


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