5,7-Dihydroxy-6-Methoxy-2-Phenyl-4H-Chromen-4-One 5,7-二羟基-6-甲氧基-2-苯基-4H-苯并吡喃-4-酮
CAS 480-11-5 MFCD02259441
化学结构图
SMILES: COC1C(O)=CC2OC(=CC(=O)C=2C=1O)C1C=CC=CC=1
化学属性
| Mol. Formula | C16H12O5 |
|---|---|
| Mol. Weight | 284.26 |
| Melting Point | 195-197 ºC |
| Density | 1.42 |
别名和识别编码
| Chemical Name | 5,7-Dihydroxy-6-Methoxy-2-Phenyl-4H-Chromen-4-One |
|---|---|
| Synonym | 5,7-Dihydroxy-6-methoxy-2-phenyl-4H-1-benzopyran-4-one 5,7-Dihydroxy-6-methoxyflavone; 6-Methoxybaicalein; Oroxylin A Oroxylin; 5,7-Dihydroxy-6-methoxyflavone; 6-Methoxybaicalein; Baicalein 6-methyl ether 千层纸素A |
| CAS Number | 480-11-5 |
| MDL Number | MFCD02259441 |
| Chemical Name Translation | 5,7-二羟基-6-甲氧基-2-苯基-4H-苯并吡喃-4-酮 |
| PubChem Substance ID | 329818889 |
| LabNetwork Molecule ID | LN01341749 |
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分类
- {SNA} Phytochemicals in Herbal Medicine or Traditional Chinese Medicine (TCM), 细胞生物学, 营养研究
- {SNA} Bioactive Small Molecules, Cell Biology, Nutrition Research, O, Phytochemicals in Herbal Medicine or Traditional Chinese Medicine (TCM)
相关文献及参考
- [2]. Dai Q, et al. Oroxylin A regulates glucose metabolism in response to hypoxic stress with the involvement of Hypoxia-inducible factor-1 in human hepatoma HepG2 cells. Mol Carcinog. 2015 Aug 10.
- [3]. Wei L, et al. Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization. Cell Death Dis. 2015 Apr 9
- Merck: 14,6878
- [1]. Zhao K, et al. Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells. J Hematol Oncol. 2015 Apr 23;8:41. http://www.ncbi.nlm.nih.gov/pubmed/25902914
- [1]. Zhao K, et al. Oroxylin A promotes PTEN-mediated negative regulation of MDM2 transcription via SIRT3-mediated deacetylation to stabilize p53 and inhibit glycolysis in wt-p53 cancer cells. J Hematol Oncol. 2015 Apr 23;8:41. http://www.ncbi.nlm.nih.gov/pubmed/25902914
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安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
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